Climate change and cascading risks from infectious disease
JC Semenza, J Rocklöv, KL Ebi - Infectious diseases and therapy, 2022 - Springer
Climate change is adversely affecting the burden of infectious disease throughout the world,
which is a health security threat. Climate-sensitive infectious disease includes vector-borne …
which is a health security threat. Climate-sensitive infectious disease includes vector-borne …
Emerging concepts and technologies in vaccine development
Despite the success of vaccination to greatly mitigate or eliminate threat of diseases caused
by pathogens, there are still known diseases and emerging pathogens for which the …
by pathogens, there are still known diseases and emerging pathogens for which the …
RTS, S/AS01 vaccine (Mosquirix™): an overview
MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
Vaccine adjuvants: from 1920 to 2015 and beyond
A Di Pasquale, S Preiss, F Tavares Da Silva, N Garçon - Vaccines, 2015 - mdpi.com
The concept of stimulating the body's immune response is the basis underlying vaccination.
Vaccines act by initiating the innate immune response and activating antigen presenting …
Vaccines act by initiating the innate immune response and activating antigen presenting …
Seven-year efficacy of RTS, S/AS01 malaria vaccine among young African children
Background The candidate malaria vaccine RTS, S/AS01 is being evaluated in order to
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …
inform a decision regarding its inclusion in routine vaccination schedules. Methods We …
Genetic diversity and protective efficacy of the RTS, S/AS01 malaria vaccine
DE Neafsey, M Juraska, T Bedford… - … England Journal of …, 2015 - Mass Medical Soc
Background The RTS, S/AS01 vaccine targets the circumsporozoite protein of Plasmodium
falciparum and has partial protective efficacy against clinical and severe malaria disease in …
falciparum and has partial protective efficacy against clinical and severe malaria disease in …
Beyond antigens and adjuvants: formulating future vaccines
The need to optimize vaccine potency while minimizing toxicity in healthy recipients has
motivated studies of the formulation of vaccines to control how, when, and where antigens …
motivated studies of the formulation of vaccines to control how, when, and where antigens …
Childhood adiposity, adult adiposity, and cardiovascular risk factors
M Juonala, CG Magnussen, GS Berenson… - … England Journal of …, 2011 - Mass Medical Soc
Background Obesity in childhood is associated with increased cardiovascular risk. It is
uncertain whether this risk is attenuated in persons who are overweight or obese as children …
uncertain whether this risk is attenuated in persons who are overweight or obese as children …
Vaccines for the 21st century
I Delany, R Rappuoli, E De Gregorio - EMBO molecular medicine, 2014 - embopress.org
In the last century, vaccination has been the most effective medical intervention to reduce
death and morbidity caused by infectious diseases. It is believed that vaccines save at least …
death and morbidity caused by infectious diseases. It is believed that vaccines save at least …
Systems analysis of protective immune responses to RTS, S malaria vaccination in humans
RTS, S is an advanced malaria vaccine candidate and confers significant protection against
Plasmodium falciparum infection in humans. Little is known about the molecular …
Plasmodium falciparum infection in humans. Little is known about the molecular …