The past two decades of research into the pathogenesis of Alzheimer disease (AD) have
been driven largely by the amyloid hypothesis; the neuroinflammation that is associated with …

Alzheimer's disease is the most prevalent cause of dementia, which is defined by the
combined presence of amyloid and tau, but researchers are gradually moving away from the …

Biochemical and neuropathological studies of brains from individuals with Alzheimer
disease (AD) provide clear evidence for an activation of inflammatory pathways, and long …

The complement system plays critical roles in development, homeostasis, and regeneration
in the central nervous system (CNS) throughout life; however, complement dysregulation in …

Communication between the immune system and the central nervous system (CNS) is
exemplified by cross‐talk between glia and neurons shown to be essential for maintaining …

Expression of proteins associated with immune function was investigated
immunohistochemically in postmortem brain and spinal cord of patients with amyotrophic …

Alzheimer's disease (AD), the most common form of dementia, is a progressive disorder
manifested by gradual memory loss and subsequent impairment in mental and behavioral …

Microglia express many leukocyte surface antigens which are upregulated in such chronic
degenerative neurological diseases as Alzheimer's disease (AD) and amyotrophic lateral …

We conducted a co-twin control study among 50 elderly twin pairs with onsets of Alzheimer's
disease (AD) separated by 3 or more years. Twenty-three male pairs (46%) were screened …

Data from clinical, electrophysiologic, neurophysiologic, neuroimaging and neuropathologic
sources indicates that the progression of brain aging and Alzheimer's disease (AD) …