The 5th edition of the World Health Organization classification of haematolymphoid tumours: lymphoid neoplasms

R Alaggio, C Amador, I Anagnostopoulos, AD Attygalle… - Leukemia, 2022 - nature.com
We herein present an overview of the upcoming 5th edition of the World Health Organization
Classification of Haematolymphoid Tumours focussing on lymphoid neoplasms. Myeloid …

Mantle cell lymphoma: 2019 update on the diagnosis, pathogenesis, prognostication, and management

P Jain, M Wang - American journal of hematology, 2019 - Wiley Online Library
Unprecedented advances in our understanding of the pathobiology, prognostication, and
therapeutic options in mantle cell lymphoma (MCL) have taken place in the last few years …

The international consensus classification of mature lymphoid neoplasms: a report from the clinical advisory committee

E Campo, ES Jaffe, JR Cook… - Blood, The Journal …, 2022 - ashpublications.org
Since the publication of the Revised European-American Classification of Lymphoid
Neoplasms in 1994, subsequent updates of the classification of lymphoid neoplasms have …

[HTML][HTML] Three-year follow-up of KTE-X19 in patients with relapsed/refractory mantle cell lymphoma, including high-risk subgroups, in the ZUMA-2 study

M Wang, J Munoz, A Goy, FL Locke… - Journal of clinical …, 2022 - journals.lww.com
Purpose Brexucabtagene autoleucel (KTE-X19) autologous anti-CD19 chimeric antigen
receptor (CAR) T-cell therapy is approved for the treatment of relapsed/refractory mantle cell …

Genomic profiling for clinical decision making in lymphoid neoplasms

L De Leval, AA Alizadeh, PL Bergsagel… - Blood, The Journal …, 2022 - ashpublications.org
With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Brexucabtagene autoleucel for relapsed or refractory mantle cell lymphoma in standard-of-care practice: results from the US lymphoma CAR T consortium

Y Wang, P Jain, FL Locke, MJ Maurer… - Journal of clinical …, 2023 - ascopubs.org
PURPOSE Brexucabtagene autoleucel (brexu-cel) is an autologous CD19-directed chimeric
antigen receptor (CAR) T-cell therapy approved for relapsed/refractory mantle cell …

Genomic and epigenomic insights into the origin, pathogenesis, and clinical behavior of mantle cell lymphoma subtypes

F Nadeu, D Martin-Garcia, G Clot… - Blood, The Journal …, 2020 - ashpublications.org
Mantle cell lymphoma (MCL) is a mature B-cell neoplasm initially driven by CCND1
rearrangement with 2 molecular subtypes, conventional MCL (cMCL) and leukemic non …

Mantle cell lymphoma in 2022—A comprehensive update on molecular pathogenesis, risk stratification, clinical approach, and current and novel treatments

P Jain, ML Wang - American journal of hematology, 2022 - Wiley Online Library
The field of mantle cell lymphoma (MCL) has witnessed remarkable progress due to
relentless advances in molecular pathogenesis, prognostication, and newer treatments …

Genomic and transcriptomic profiling reveals distinct molecular subsets associated with outcomes in mantle cell lymphoma

S Yi, Y Yan, M Jin, S Bhattacharya… - The Journal of …, 2022 - Am Soc Clin Investig
Mantle cell lymphoma (MCL) is a phenotypically and genetically heterogeneous malignancy
in which the genetic alterations determining clinical indications are not fully understood …

Dynamic molecular monitoring reveals that SWI–SNF mutations mediate resistance to ibrutinib plus venetoclax in mantle cell lymphoma

R Agarwal, YC Chan, CS Tam, T Hunter… - Nature medicine, 2019 - nature.com
Ibrutinib plus venetoclax is a highly effective combination in mantle cell lymphoma.
However, strategies to enable the evaluation of therapeutic response are required. Our …