▪ Abstract Bioluminescence has evolved independently many times; thus the responsible
genes are unrelated in bacteria, unicellular algae, coelenterates, beetles, fishes, and others …

Understanding luciferase enzymology and the structure of compounds that modulate
luciferase activity can be used to improve the design of luminescence-based assays. This …

The crystal structure of recombinant wild-type green fluorescent protein (GFP) has been
solved to a resolution of 1.9 Å by multiwavelength anomalous dispersion phasing methods …

This book, written by a distinguished scientist in the field, provides a comprehensive
overview of the biochemical aspects of all luminous organisms currently known. It is the first …

Background: Firefly luciferase is a 62 kDa protein that catalyzes the production of light. In the
presence of MgATP and molecular oxygen, the enzyme oxidizes its substrate, firefly luciferin …

Many different organisms, ranging from bacteria and fungi to fireflies and fish, are endowed
with the ability to emit light, but the bioluminescent systems are not evolutionarily conserved …

The crystal structure of DsRed, a red fluorescent protein from a corallimorpharian, has been
determined at 2.0-Å resolution by multiple-wavelength anomalous dispersion and …

Luciferases are the enzymes that catalyze the reactions that produce light in
bioluminescence. Whereas the oxidative mechanism which leads to light emission is similar …

Luciferase is a general term for enzymes catalyzing visible light emission by living
organisms (bioluminescence). The studies carried out with Photinus pyralis (firefly) …

Significant advances have occurred regarding our knowledge of firefly luciferase
mechanisms. Although most of this progress was an outcome of molecular biology and …