Mammalian eggs (oocytes) are formed during fetal life and establish associations with
somatic cells to form primordial follicles that create a store of germ cells (the primordial pool) …

BACKGROUND A normal chromosomal constitution defined through PGT-A assessing all
chromosomes on trophectoderm (TE) biopsies represents the strongest predictor of embryo …

STUDY QUESTION Which add-ons are safe and effective to be used in ART treatment?
SUMMARY ANSWER Forty-two recommendations were formulated on the use of add-ons in …

The Imperative of Responsible Innovation in Reproductive Medicine Page 1 Sounding Board The
new england journal of medicine n engl j med 385;22 nejm.org November 25, 2021 2096 The …

In IVF cycles, the application of aneuploidy testing at the blastocyst stage is quickly growing,
and the latest reports estimate almost half of cycles in the US undergo preimplantation …

Human female fertility and reproductive lifespan decrease significantly with age, resulting in
an extended post-reproductive period. The central dogma in human female reproduction …

STUDY QUESTION What are the outcomes for patients who choose to move embryos
diagnosed as abnormal by preimplantation genetic testing for aneuploidy (PGT-A) to a new …

Pregnancy is established during the periconceptional period as a continuum beginning with
blastocyst attachment to the endometrial epithelial surface followed by embryo invasion and …

Abstract The American Society for Reproductive Medicine estimates that fewer than a
quarter of infertile couples have sufficient access to infertility care. Insurers in the United …

Numerous chronic diseases have a substantial hereditary component. Recent advances in
human genetics have allowed the extent of this to be quantified via genome-wide …