Circular RNAs: biogenesis, biological functions, and roles in myocardial infarction

J Li, Y Han, S Wang, X Wu, J Cao, T Sun - International journal of …, 2023 - mdpi.com
Non-coding RNAs have been excavated as important cardiac function modulators and
linked to heart diseases. Significant advances have been obtained in illuminating the effects …

The tumorigenic role of circular RNA-MicroRNA Axis in cancer

WR Kim, EG Park, DH Lee, YJ Lee, WH Bae… - International Journal of …, 2023 - mdpi.com
Circular RNAs (circRNAs) are a class of endogenous RNAs that control gene expression at
the transcriptional and post-transcriptional levels. Recent studies have increasingly …

Targeting delivery of miR-146a via IMTP modified milk exosomes exerted cardioprotective effects by inhibiting NF-κB signaling pathway after myocardial ischemia …

W Meng, J Zhu, Y Wang, C Shao, X Li, P Lu… - Journal of …, 2024 - Springer
Reperfusion therapy is critical for saving heart muscle after myocardial infarction, but the
process of restoring blood flow can itself exacerbate injury to the myocardium. This …

Noncoding RNAs in the COVID-19 saga: an untold story

M Maqbool, MS Hussain, NK Shaikh, A Sultana… - Viral …, 2024 - liebertpub.com
In late 2019, the SARS-CoV-2 virus emerged as the cause of COVID-19, triggering a
worldwide pandemic of unprecedented scale. A detailed comprehension is being …

Clinical significance of MicroRNAs, long non-coding RNAs, and CircRNAs in cardiovascular diseases

DD Singh, Y Kim, SA Choi, I Han, DK Yadav - Cells, 2023 - mdpi.com
Based on recent research, the non-coding genome is essential for controlling genes and
genetic programming during development, as well as for health and cardiovascular …

Epigenetic regulation of programmed cell death in hypoxia-induced pulmonary arterial hypertension

Y Jiang, S Song, J Liu, L Zhang, X Guo, J Lu… - Frontiers in …, 2023 - frontiersin.org
Pulmonary arterial hypertension (PAH) is a severe progressive disease that may cause early
right ventricular failure and eventual cardiac failure. The pathogenesis of PAH involves …

Endothelial cell dysfunction in cardiac disease: driver or consequence?

JD Allbritton-King, G García-Cardeña - Frontiers in Cell and …, 2023 - frontiersin.org
The vascular endothelium is a multifunctional cellular system which directly influences blood
components and cells within the vessel wall in a given tissue. Importantly, this cellular …

Circular RNAs as a diagnostic and therapeutic target in cardiovascular diseases

VHA Joaquim, NP Pereira, T Fernandes… - International journal of …, 2023 - mdpi.com
Circular RNAs (circRNAs) are a family of noncoding RNAs (ncRNAs) that are endogenous
and widely distributed in different species, performing several functions, mainly their …

Mechanism of heart failure after myocardial infarction

H Jiang, T Fang, Z Cheng - Journal of International Medical …, 2023 - journals.sagepub.com
Despite the widespread use of early revascularization and drugs to regulate the
neuroendocrine system, the impact of such measures on alleviating the development of …

The role of ncRNAs in cardiac infarction and regeneration

S Caño-Carrillo, E Lozano-Velasco… - Journal of …, 2023 - mdpi.com
Myocardial infarction is the most prevalent cardiovascular disease worldwide, and it is
defined as cardiomyocyte cell death due to a lack of oxygen supply. Such a temporary …