Mesenchymal stromal cells (MSCs) for basic research and clinical applications are
manufactured and developed as unique cell products by many different manufacturers and …

Regenerative medicine is extensively interested in developing cell therapies using
mesenchymal stem cells (MSCs), with applications to several aging-associated diseases …

Adult mesenchymal stem cells are a resource for autologous and allogeneic cell therapies
for immune-modulation and regenerative medicine. However, patients most in need of such …

Culture media for therapeutic cell preparations—such as mesenchymal stromal cells (MSCs)—
usually comprise serum additives. Traditionally, fetal bovine serum is supplemented in basic …

Multipotent mesenchymal stromal cells (MSCs) are tested in numerous clinical trials.
Questions have been raised concerning fate and function of these therapeutic cells after …

Given the observed efficacy of culture‐expanded multipotential stromal cells, also termed
mesenchymal stem cells (MSCs), in the treatment of graft‐versus host and cardiac disease, it …

All tissues of the organism are affected by aging. This process is associated with epigenetic
modifications such as methylation changes at specific cytosine residues in the DNA (CpG …

Tissue resident mesenchymal stem cells (MSCs) are known to participate in tissue
regeneration that follows cell turnover, apoptosis, or necrosis. It has been long known that …

Bone marrow-derived human mesenchymal stem cells (BM-hMSCs) represent a promising
cell-based therapy for a number of degenerative conditions. Many applications require cell …

Kawai M, de Paula FJA, Rosen CJ (Osaka Medical Center and Research Institute for
Maternal and Child Health, Izumi, Osaka, Japan; University of São Paulo, Ribeirão Preto …