An overview of the molecular mechanisms of recombinational DNA repair

SC Kowalczykowski - Cold Spring Harbor Perspectives …, 2015 - cshperspectives.cshlp.org
Recombinational DNA repair is a universal aspect of DNA metabolism and is essential for
genomic integrity. It is a template-directed process that uses a second chromosomal copy …

[HTML][HTML] Properties and behavior of carbon nanomaterials when interfacing neuronal cells: How far have we come?

R Rauti, M Musto, S Bosi, M Prato, L Ballerini - Carbon, 2019 - Elsevier
In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …

[HTML][HTML] Homologous recombination in DNA repair and DNA damage tolerance

X Li, WD Heyer - Cell research, 2008 - nature.com
Homologous recombination (HR) comprises a series of interrelated pathways that function in
the repair of DNA double-stranded breaks (DSBs) and interstrand crosslinks (ICLs). In …

Advances in single-molecule fluorescence methods for molecular biology

C Joo, H Balci, Y Ishitsuka, C Buranachai… - Annu. Rev …, 2008 - annualreviews.org
Ever since their introduction two decades ago, single-molecule (SM) fluorescence methods
have matured and branched out to address numerous biological questions, which were …

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells

JM Mason, K Dusad, WD Wright, J Grubb… - Nucleic acids …, 2015 - academic.oup.com
The RAD54 family DNA translocases have several biochemical activities. One activity,
demonstrated previously for the budding yeast translocases, is ATPase-dependent …

Mechanisms and principles of homology search during recombination

J Renkawitz, CA Lademann, S Jentsch - Nature Reviews Molecular Cell …, 2014 - nature.com
Homologous recombination is crucial for genome stability and for genetic exchange.
Although our knowledge of the principle steps in recombination and its machinery is well …

Optical tweezers analysis of DNA–protein complexes

I Heller, TP Hoekstra, GA King, EJG Peterman… - Chemical …, 2014 - ACS Publications
Cellular DNA is continuously engaged in a molecular dance with many accessory proteins.
These proteins are responsible for orchestrating the storage, maintenance, and transfer of …

[HTML][HTML] Rad54 drives ATP hydrolysis-dependent DNA sequence alignment during homologous recombination

JB Crickard, CJ Moevus, Y Kwon, P Sung, EC Greene - Cell, 2020 - cell.com
Homologous recombination (HR) helps maintain genome integrity, and HR defects give rise
to disease, especially cancer. During HR, damaged DNA must be aligned with an …

Cohesins localize with CTCF at the KSHV latency control region and at cellular c‐myc and H19/Igf2 insulators

W Stedman, H Kang, S Lin, JL Kissil… - The EMBO …, 2008 - embopress.org
Cohesins, which mediate sister chromatin cohesion, and CTCF, which functions at
chromatin boundaries, play key roles in the structural and functional organization of …

Role of Rad51 and DNA repair in cancer: A molecular perspective

E Laurini, D Marson, A Fermeglia, S Aulic… - Pharmacology & …, 2020 - Elsevier
The maintenance of genome integrity is essential for any organism survival and for the
inheritance of traits to offspring. To the purpose, cells have developed a complex DNA repair …