Modulation of the hypothalamic-pituitary-adrenal axis by early life stress exposure
M Van Bodegom, JR Homberg… - Frontiers in cellular …, 2017 - frontiersin.org
Exposure to stress during critical periods in development can have severe long-term
consequences, increasing overall risk on psychopathology. One of the key stress response …
consequences, increasing overall risk on psychopathology. One of the key stress response …
The epigenetic link between prenatal adverse environments and neurodevelopmental disorders
M Kundakovic, I Jaric - Genes, 2017 - mdpi.com
Prenatal adverse environments, such as maternal stress, toxicological exposures, and viral
infections, can disrupt normal brain development and contribute to neurodevelopmental …
infections, can disrupt normal brain development and contribute to neurodevelopmental …
Epigenetic inheritance: concepts, mechanisms and perspectives
Parents' stressful experiences can influence an offspring's vulnerability to many pathological
conditions, including psychopathologies, and their effects may even endure for several …
conditions, including psychopathologies, and their effects may even endure for several …
Transgenerational epigenetic inheritance in mammals: how good is the evidence?
SD van Otterdijk, KB Michels - The FASEB Journal, 2016 - Wiley Online Library
Epigenetics plays an important role in orchestrating key biologic processes. Epigenetic
marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are …
marks, including DNA methylation, histones, chromatin structure, and noncoding RNAs, are …
Neurodevelopmental disorders and environmental toxicants: epigenetics as an underlying mechanism
NQV Tran, K Miyake - International journal of genomics, 2017 - Wiley Online Library
The increasing prevalence of neurodevelopmental disorders, especially autism spectrum
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …
disorders (ASD) and attention deficit hyperactivity disorder (ADHD), calls for more research …
The relationships between stress, mental disorders, and epigenetic regulation of BDNF
Z Miao, Y Wang, Z Sun - International journal of molecular sciences, 2020 - mdpi.com
Brain-derived neurotrophic factor (BDNF), a critical member of the neurotrophic family, plays
an important role in multiple stress-related mental disorders. Although alterations in BDNF in …
an important role in multiple stress-related mental disorders. Although alterations in BDNF in …
A comprehensive review of genetic and epigenetic mechanisms that regulate BDNF expression and function with relevance to major depressive disorder
Major depressive disorder (MDD) is a mood disorder that affects behavior and impairs
cognition. A gene potentially important to this disorder is the brain derived neurotrophic …
cognition. A gene potentially important to this disorder is the brain derived neurotrophic …
The epigenetic impacts of social stress: how does social adversity become biologically embedded?
VT Cunliffe - Epigenomics, 2016 - Taylor & Francis
Epigenetic mechanisms are implicated in the processes through which social stressors
erode health in humans and other animals. Here I review progress in elucidating the …
erode health in humans and other animals. Here I review progress in elucidating the …
An ecologist's guide for studying DNA methylation variation in wild vertebrates
The field of molecular biology is advancing fast with new powerful technologies, sequencing
methods and analysis software being developed constantly. Commonly used tools originally …
methods and analysis software being developed constantly. Commonly used tools originally …
Transgenerational plasticity in the context of predator-prey interactions
Almost all animal species are engaged in predator-prey interactions. These interactions,
variable in time and space, favor the emergence and evolution of phenotypic plasticity …
variable in time and space, favor the emergence and evolution of phenotypic plasticity …