Recent findings point toward diet having a major impact on human health. Diets can either
affect the gut microbiota resulting in alterations in the host's physiological responses or by …

Vitamin A metabolite retinoic acid (RA) plays important roles in cell growth, differentiation,
organogenesis, and reproduction and a key role in mucosal immune responses. RA …

Recent years have seen a renaissance in the research linking inflammation and cancer with
immune cells playing a central role in smouldering inflammation in the tumor …

The intestinal immune system is emerging as an important contributor to obesity-related
insulin resistance, but the role of intestinal B cells in this context is unclear. Here, we show …

A leaky gut has been observed in a number of autoimmune diseases including type 1
diabetes, multiple sclerosis, inflammatory bowel disease, and systemic lupus …

Retinoids (vitamin A) have been reported extensively for anti-cancer properties due to their
high receptor-binding affinities and gene regulation abilities. However, the anti-cancer …

Retinoic acid (RA) agents possess anti-tumor activity through their ability to induce cellular
differentiation. However, retinoids have not yet been translated into effective systemic …

Ferroptosis is programmed cell death induced by iron-driven lipid peroxidation. Numerous
studies have shown that ferroptosis is implicated in the progression of colorectal cancer …

Background Host-microbial interactions are expected to affect species' adaptability to
climate change but have rarely been explored in ectothermic animals. Some studies have …

The micronutrient vitamin A refers to a group of compounds with pleiotropic effects on
human health. These molecules can modulate biological functions, including development …