The flavonoid quercetin is frequently found in low amounts as a secondary plant metabolite
in fruits and vegetables. Isolated quercetin is also marketed as a dietary supplement, mostly …

Great interest is currently centered on the biologic activities of quercetin a polyphenol
belonging to the class of flavonoids, natural products well known for their beneficial effects …

Understanding transporter-mediated drug–drug interactions (DDIs) for investigational
agents is important during drug development to assess DDI liability, its clinical relevance …

Quercetin is categorized as a flavonol, one of the six subclasses of flavonoid compounds
(Table 1). Flavonoids are a family of plant compounds that share a similar flavone backbone …

The main mechanism for drug-drug interaction is displacement reaction of ligands from their
protein binding sites. The aim of this study was to evaluate anticancer drug sorafenib …

Abstract In India, Ayurveda has made a major contribution to the drug discovery process with
new means of identifying active compounds. Recent advancement in bioavailability …

This review centers on recent findings with respect to modulating cancer multidrug
resistance (MDR) with the well-known flavonoid quercetin. After a short introduction of …

Cancer is a problem of global importance, since the incidence is increasing worldwide and
therapeutic options are generally limited. Thus, it becomes imperative to find new …

This study was designed to examine the interaction of neratinib (NRB) with human serum
albumin (HSA) in presence of flavonoids quercetin and rutin. Both quercetin and rutin can …

In recent years, an increasing number of clinical drug–drug interactions (DDIs) have been
attributed to inhibition of intestinal organic anion-transporting polypeptides (OATPs); …