Epigenetics in Knee Osteoarthritis: A 2020–2023 Update Systematic Review

D Caldo, E Massarini, M Rucci, S Deaglio, R Ferracini - Life, 2024 - mdpi.com
Osteoarthritis is a leading cause of disability in the world. The scientific literature highlights
the critical importance of epigenetic regulatory effects, intertwined with biomechanical and …

Epigenetics as a mediator of genetic risk in osteoarthritis: role during development, homeostasis, aging, and disease progression

D Richard, TD Capellini… - American Journal of …, 2023 - journals.physiology.org
The identification of genomic loci that are associated with osteoarthritis (OA) has provided a
starting point for understanding how genetic variation activates catabolic processes in the …

Differential chondrogenic differentiation between iPSC derived from healthy and OA cartilage is associated with changes in epigenetic regulation and metabolic …

NM Khan, ME Diaz-Hernandez, S Chihab… - Elife, 2023 - elifesciences.org
Induced pluripotent stem cells (iPSCs) are potential cell sources for regenerative medicine.
The iPSCs exhibit a preference for lineage differentiation to the donor cell type indicating the …

Epigenetic regulation of chondrocytes and subchondral bone in osteoarthritis

HC Ball, AL Alejo, TK Samson, AM Alejo, FF Safadi - Life, 2022 - mdpi.com
The aim of this review is to provide an updated review of the epigenetic factors involved in
the onset and development of osteoarthritis (OA). OA is a prevalent degenerative joint …

[HTML][HTML] Enrichment of genomic pathways based on differential DNA methylation profiles associated with knee osteoarthritis pain

S Montesino-Goicolea, L Meng, A Rani, Z Huo… - Neurobiology of Pain, 2022 - Elsevier
Our study aimed to identify differentially methylated regions (ie, genomic region where
multiple adjacent CpG sites show differential methylation) and their enriched genomic …

[HTML][HTML] Musculoskeletal Biology and Bioengineering: Epigenetics as a mediator of genetic risk in osteoarthritis: role during development, homeostasis, aging, and …

D Richard, TD Capellini… - American Journal of …, 2023 - ncbi.nlm.nih.gov
The identification of genomic loci that are associated with osteoarthritis (OA) has provided a
starting point for understanding how genetic variation activates catabolic processes in the …

Author list: 8

D Richard, TD Capellini, BO Diekman - journals.physiology.org
55 The advent of modern-day medical care, paired with public health policies and increased
56 standards of living, have led to an 'epidemiological transition'in the drivers of mortality (1) …

[HTML][HTML] Herbal Formulations Containing Tamarindus indica Seed Extract Significantly Improved Joint Mobility and Reduced Musculoskeletal Pain in Subjects with …

T Woosley - naturalhealthresearch.org
Written by Taylor Woosley, Staff Writer. Results of the 56-day study demonstrate the efficacy
of tamarind-containing botanical compositions on alleviating pain and improving joint …