Microtubules are pivotal in diverse cellular functions encompassing cell signaling,
morphology, intracellular trafficking, and cell mitosis/division. They are validated targets for …

Cytoskeleton proteins have been long recognized as structural proteins that provide the
necessary mechanical architecture for cell development and tissue homeostasis. With the …

The principal cause of death in cancer patients is metastasis, which remains an unresolved
problem. Conventionally, metastatic dissemination is linked to actomyosin‐driven cell …

Digestive system cancer and COVID-19 significantly affect the digestive system, but the
mechanism of interaction between COVID-19 and the digestive system cancers has not …

Background The nuclear distribution E homologue 1 (NDE1) is a crucial dynein binding
partner. The NDE1 protein has the potential to disrupt the normal functioning of …

Angiosarcoma is a rare refractory soft-tissue tumor with a poor prognosis and is treated by
radiotherapy. The fibroblast growth factor 1 (FGF1) mutant, with enhanced thermostability …

Glial cells provide physical and chemical support and protection for neurons and for the
extracellular compartments of neural tissue through secretion of soluble factors, insoluble …

Head and neck squamous cell carcinoma (HNSC) is one of the most lethal malignancies
around the globe. Due to its complex nature, the diagnostic and prognostic signatures of …

Dynein-mediated cargo transport plays pivotal roles in a variety of essential cellular
activities, including vesicle trafficking, organelle and nucleus positioning, mitosis and …

Kinesin motors play diverse roles in cells, including spindle assembly and chromosome
segregation. Each kinesin has three general domains: the motor head, neck, and tail. As …