[HTML][HTML] High ventilation breathwork practices: An overview of their effects, mechanisms, and considerations for clinical applications

GW Fincham, A Kartar, MV Uthaug, B Anderson… - Neuroscience & …, 2023 - Elsevier
Abstract High Ventilation Breathwork (HVB) refers to practices employing specific volitional
manipulation of breathing, with a long history of use to relieve various forms of psychological …

11β‐Hydroxysteroid dehydrogenase and the brain: Not (yet) lost in translation

J Seckl - Journal of Internal Medicine, 2024 - Wiley Online Library
beta‐hydroxysteroid dehydrogenases (11β‐HSDs) catalyse the conversion of active 11‐
hydroxy glucocorticoids (cortisol, corticosterone) and their inert 11‐keto forms (cortisone, 11 …

The Historical Progression of Positron Emission Tomography Research in Neuroendocrinology

J Bini - Frontiers in Neuroendocrinology, 2023 - Elsevier
The rapid and continual development of a number of radiopharmaceuticals targeting
different receptor, enzyme and small molecule systems has fostered Positron Emission …

Microglia-mediated neuroimmune suppression in PTSD is associated with anhedonia

R Bonomi, AT Hillmer, E Woodcock, S Bhatt… - Proceedings of the …, 2024 - pnas.org
Dynamic brain immune function in individuals with posttraumatic stress disorder is rarely
studied, despite evidence of peripheral immune dysfunction. Positron emission tomography …

Mitochondrial dysfunction as a possible trigger of neuroinflammation at post-traumatic stress disorder (PTSD)

TR Dmytriv, SA Tsiumpala, HM Semchyshyn… - Frontiers in …, 2023 - frontiersin.org
Post-traumatic stress disorder (PTSD) is a neuropsychiatric disorder that occurs in
approximately 15% of people as a result of some traumatic events. The main symptoms are …

[HTML][HTML] 11β-Hydroxysteroid dehydrogenase 1 deficiency prevents PTSD-like memory in young adult mice

N Wheelan, JR Seckl, JLW Yau - Psychoneuroendocrinology, 2022 - Elsevier
Post-traumatic stress disorder (PTSD) is characterized by the co-existence of a persistent
strong memory of the traumatic experience and amnesia for the peritraumatic context. Most …

The glucocorticoid footprint on the memory engram

F Jeanneteau, L Coutellier - Current opinion in endocrine and metabolic …, 2022 - Elsevier
The complexity of the classical inverted U-shaped relationship between cortisol levels and
responses transposable to stress reactivity has led to an incomplete understanding of the …

Investigating TSPO levels in occupation-related posttraumatic stress disorder

SE Watling, T Gill, EV Gaudette, JD Richardson… - Scientific reports, 2023 - nature.com
Microglia are immune brain cells implicated in stress-related mental illnesses including
posttraumatic stress disorder (PTSD). Their role in the pathophysiology of PTSD, and on …

[HTML][HTML] Imaging a putative marker of brain cortisol regulation in alcohol use disorder

TL Verplaetse, AT Hillmer, S Bhatt, A Rusowicz… - Neurobiology of …, 2024 - Elsevier
Background Stress is a potent activator of the hypothalamic-pituitary-adrenal (HPA) axis,
initiating the release of glucocorticoid hormones, such as cortisol. Alcohol consumption can …

Stress and the risk of Alzheimer dementia: Can deconstructed engrams be rebuilt?

F Jeanneteau - Journal of Neuroendocrinology, 2023 - Wiley Online Library
The exact neuropathological mechanism by which the dementia process unfolds is under
intense scrutiny. The disease affects about 38 million people worldwide, 70% of which are …