With the advent of population aging, aging-related diseases have become a challenge for
governments worldwide. Sarcopenia has defined as a clinical syndrome associated with …

Early atherosclerosis features functional and structural changes in the endothelial barrier
function that affect the traffic of molecules and solutes between the vessel lumen and the …

Background: Chronic activation of the innate immune system drives inflammation and
contributes directly to atherosclerosis. We previously showed that macrophages in the …

Characterized by a surplus of whole-body adiposity, obesity is strongly associated with the
prognosis of atherosclerosis, a hallmark of coronary artery disease (CAD) and the major …

Heart disease is a leading cause of death with unmet clinical needs for targeted treatment
options. Tumor necrosis factor alpha (TNF-α) represents a master pro-inflammatory cytokine …

Cardiovascular diseases (CVD) are an important cause of death worldwide. Anthocyanins
are a subgroup of flavonoids found in berries, flowers, fruits and leaves. In epidemiological …

Low plasma testosterone (T) levels correlated with metabolic syndrome, cardiovascular
diseases, and increased mortality risk. T exerts a significant effect on the regulation of …

Obesity is characterized by an increase in body weight associated with an exaggerated
enlargement of the adipose tissue. Obesity has serious negative effects because it is …

Cardiovascular diseases can be considered the most important cause of death in diabetic
population and diabetes can in turn increase the risk of cardiovascular events. Inflammation …

Signaling pathways induced by the proinflammatory cytokine tumor necrosis factor alpha
(TNF-α) play a key role in the cellular responses to inflammation and injury. In the …