Targeted imaging of bacterial infections: advances, hurdles and hopes

M van Oosten, M Hahn, LMA Crane… - FEMS microbiology …, 2015 - academic.oup.com
Bacterial infections represent an increasing problem in modern health care, in particular due
to ageing populations and accumulating bacterial resistance to antibiotics. Diagnosis is …

Mesoporous silica materials as drug delivery:“The Nightmare” of bacterial infection

M Martínez-Carmona, YK Gun'ko, M Vallet-Regí - Pharmaceutics, 2018 - mdpi.com
Mesoporous silica materials (MSM) have a great surface area and a high pore volume,
meaning that they consequently have a large loading capacity, and have been …

Bacteria eat nanoprobes for aggregation-enhanced imaging and killing diverse microorganisms

Y Yang, B Chu, J Cheng, J Tang, B Song… - Nature …, 2022 - nature.com
Currently optical-based techniques for in vivo microbial population imaging are limited by
low imaging depth and highly light-scattering tissue; and moreover, are generally effective …

Maltotriose-based probes for fluorescence and photoacoustic imaging of bacterial infections

A Zlitni, G Gowrishankar, I Steinberg… - Nature …, 2020 - nature.com
Currently, there are no non-invasive tools to accurately diagnose wound and surgical site
infections before they become systemic or cause significant anatomical damage …

Multifunctional Au nano-bridged nanogap probes as ICP-MS/SERS dual-signal tags and signal amplifiers for bacteria discriminating, quantitative detecting and …

X Huang, Z Zhang, L Chen, Y Lin, R Zeng, J Xu… - Biosensors and …, 2022 - Elsevier
Ultra-sensitive detection of pathogenic bacteria is of great significance in the early stage of
bacterial infections and treatment. In this work, we report a novel strategy using …

One-step synthesis of biofunctional carbon quantum dots for bacterial labeling

CI Weng, HT Chang, CH Lin, YW Shen… - Biosensors and …, 2015 - Elsevier
In this study, we used a simple one-step dry heating method to synthesize mannose-
modified fluorescent carbon quantum dots (Man-CQDs) from solid ammonium citrate and …

Concanavalin A-targeted mesoporous silica nanoparticles for infection treatment

M Martínez-Carmona, I Izquierdo-Barba, M Colilla… - Acta biomaterialia, 2019 - Elsevier
The ability of bacteria to form biofilms hinders any conventional treatment for chronic
infections and has serious socio-economic implications. For this purpose, a nanocarrier …

Imaging in chronic wound diagnostics

S Li, AH Mohamedi, J Senkowsky, A Nair… - Advances in wound …, 2020 - liebertpub.com
Significance: Chronic wounds affect millions of patients worldwide, placing a huge burden
on health care resources. Although significant progress has been made in the development …

Development of fluorescent probes targeting the cell wall of pathogenic bacteria

W Liu, L Miao, X Li, Z Xu - Coordination Chemistry Reviews, 2021 - Elsevier
Contamination of pathogenic bacteria seriously threatens human health and safety, and the
types and pathogenicity of bacteria are closely related to cell walls. Fluorescent probes can …

Investigation of 6-[18F]-Fluoromaltose as a Novel PET Tracer for Imaging Bacterial Infection

G Gowrishankar, M Namavari, EB Jouannot, A Hoehne… - PloS one, 2014 - journals.plos.org
Despite advances in the field of nuclear medicine, the imaging of bacterial infections has
remained a challenge. The existing reagents suffer from poor sensitivity and specificity. In …