The stimulator of interferon genes (STING) cellular signaling pathway is a promising target
for cancer immunotherapy. Activation of the intracellular STING protein triggers the …

Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …

With the continuous development of immunotherapy, researchers have paid more attention
to the specific immune regulatory mechanisms of various immune responses in different …

Polymeric microneedle (MN) systems are interesting transdermal drug delivery systems
because of their controlled drug delivery, tunable properties, and ease of patient self …

Abstract STING (Stimulator of Interferon Genes) agonists have emerged as promising agents
in the field of cancer immunotherapy, owing to their excellent capacity to activate the innate …

Gene therapy is a critical constituent of treatment approaches for genetic diseases and has
gained tremendous attention. Treating and preventing diseases at the genetic level using …

Highlights•Allergen immunotherapy is the only approach for inducing long-term immune
tolerance toward allergens.•Skin-based allergen therapy shows promise, given the …

The prevalence of peanut allergies has escalated over the last 20 years, yet there are no
FDA approved treatments for peanut allergies. In this study we evaluated the potential of …

As a prospective influenza vaccination platform, a microneedle patch offers advantages
such as self-administration and reduction of needle-phobia-associated vaccination …

Cyclic dinucleotides (CDNs), originally discovered as bacterial second messengers, play
critical roles in bacterial signal transduction, cellular processes, biofilm formation, and …