[HTML][HTML] A guide to the organ-on-a-chip

CM Leung, P De Haan… - Nature Reviews …, 2022 - nature.com
Abstract Organs-on-chips (OoCs) are systems containing engineered or natural miniature
tissues grown inside microfluidic chips. To better mimic human physiology, the chips are …

Beyond polydimethylsiloxane: alternative materials for fabrication of organ-on-a-chip devices and microphysiological systems

SB Campbell, Q Wu, J Yazbeck, C Liu… - ACS biomaterials …, 2020 - ACS Publications
Polydimethylsiloxane (PDMS) is the predominant material used for organ-on-a-chip devices
and microphysiological systems (MPSs) due to its ease-of-use, elasticity, optical …

Advances in Hydrogels in Organoids and Organs‐on‐a‐Chip

H Liu, Y Wang, K Cui, Y Guo, X Zhang… - Advanced …, 2019 - Wiley Online Library
Significant advances in materials, microscale technology, and stem cell biology have
enabled the construction of 3D tissues and organs, which will ultimately lead to more …

[HTML][HTML] Regeneration of dermis: scarring and cells involved

AL Rippa, EP Kalabusheva, EA Vorotelyak - Cells, 2019 - mdpi.com
There are many studies on certain skin cell specifications and their contribution to wound
healing. In this review, we provide an overview of dermal cell heterogeneity and their …

Applications and delivery mechanisms of hyaluronic acid used for topical/transdermal delivery–a review

J Zhu, X Tang, Y Jia, CT Ho, Q Huang - International journal of …, 2020 - Elsevier
The purpose of this review is to introduce the functionalities of hyaluronic acid (HA) and its
potential application as an effective carrier for topical/transdermal delivery. Specifically …

[HTML][HTML] Organs-on-a-chip module: a review from the development and applications perspective

JE Sosa-Hernández, AM Villalba-Rodríguez… - Micromachines, 2018 - mdpi.com
In recent years, ever-increasing scientific knowledge and modern high-tech advancements
in micro-and nano-scales fabrication technologies have impacted significantly on various …

[HTML][HTML] Breakthroughs and applications of organ-on-a-chip technology

MC Koyilot, P Natarajan, CR Hunt, S Sivarajkumar… - Cells, 2022 - mdpi.com
Organ-on-a-chip (OOAC) is an emerging technology based on microfluid platforms and in
vitro cell culture that has a promising future in the healthcare industry. The numerous …

Gut-on-a-chip: Current progress and future opportunities

N Ashammakhi, R Nasiri, NR De Barros, P Tebon… - Biomaterials, 2020 - Elsevier
Organ-on-a-chip technology tries to mimic the complexity of native tissues in vitro. Important
progress has recently been made in using this technology to study the gut with and without …

Recent advances in body-on-a-chip systems

JH Sung, YI Wang, N Narasimhan Sriram… - Analytical …, 2018 - ACS Publications
Microphysiological systems (MPS, also known as “organ-on-a-chip”,“body-on-a-chip”, or
“human-on-a-chip”) have emerged over the last 15 years as attractive systems to probe …

[HTML][HTML] Organs-on-chips technologies–A guide from disease models to opportunities for drug development

AG Monteduro, S Rizzato, G Caragnano… - Biosensors and …, 2023 - Elsevier
Current in-vitro 2D cultures and animal models present severe limitations in recapitulating
human physiopathology with striking discrepancies in estimating drug efficacy and side …