The extracellular matrix (ECM) constitutes a highly dynamic three-dimensional structural
network comprised of macromolecules, such as proteoglycans/glycosaminoglycans …

Extracellular matrix is a highly dynamic macromolecular network. Proteoglycans are major
components of extracellular matrix playing key roles in its structural organization and cell …

Mammalian skin comprises a multi-layered epithelium, the epidermis, and an underlying
connective tissue, the dermis. The epidermal extracellular matrix is a basement membrane …

Here, we interrogated head and neck cancer (HNSCC) specimens (n= 12) to examine if
different metabolic compartments (oxidative vs. glycolytic) co-exist in human tumors. A large …

Individual human epidermal cells differ in their self-renewal ability. To uncover the molecular
basis for this heterogeneity, we performed genome-wide pooled RNA interference screens …

Retrograde flow of menstrual blood cells during menstruation is considered as the dominant
theory for the development of endometriosis. Moreover, current evidence suggests that …

Malignant neoplasms may be composed of several cell groups, including cancer stem cells
(CSC). These cells have been related with the capacity of metastasis, relapse and …

This article explores and summarizes recent progress in and the characterization of main
players in the regulation and cyclic regeneration of hair follicles. The review discusses …

Signalling by the epidermal growth factor receptor (EGFR) controls morphogenesis and/or
homeostasis of several tissues from worms to mammals. The correct execution of these …

NG2/CSPG4 is an unusual cell-membrane integral proteoglycan widely recognized to be a
prognostic factor, a valuable tool for ex vivo and non-invasive molecular diagnostics and, by …