Different sources of mesenchymal stem cells for tissue regeneration: a guide to identifying the most favorable one in orthopedics and dentistry applications

VJ Costela-Ruiz, L Melguizo-Rodríguez… - International Journal of …, 2022 - mdpi.com
The success of regenerative medicine in various clinical applications depends on the
appropriate selection of the source of mesenchymal stem cells (MSCs). Indeed, the source …

Pretreated mesenchymal stem cells and their secretome: enhanced immunotherapeutic strategies

Y Su, C Xu, W Cheng, Y Zhao, L Sui… - International journal of …, 2023 - mdpi.com
Mesenchymal stem cells (MSCs) with self-renewing, multilineage differentiation and
immunomodulatory properties, have been extensively studied in the field of regenerative …

NAD+/NADH redox alterations reconfigure metabolism and rejuvenate senescent human mesenchymal stem cells in vitro

X Yuan, Y Liu, BM Bijonowski, AC Tsai, Q Fu… - Communications …, 2020 - nature.com
Human mesenchymal stem cells (hMSCs) promote endogenous tissue regeneration and
have become a promising candidate for cell therapy. However, in vitro culture expansion of …

Mesenchymal stromal cells: heterogeneity and therapeutical applications

M Ouzin, G Kogler - Cells, 2023 - mdpi.com
Mesenchymal stromal cells nowadays emerge as a major player in the field of regenerative
medicine and translational research. They constitute, with their derived products, the most …

Melatonin plays critical role in mesenchymal stem cell-based regenerative medicine in vitro and in vivo

C Hu, L Li - Stem cell research & therapy, 2019 - Springer
Although stem cells have emerged as promising sources for regenerative medicine, there
are many potential safety hazards for their clinical application, including tumorigenicity, an …

In Vitro Culture Expansion Shifts the Immune Phenotype of Human Adipose-Derived Mesenchymal Stem Cells

R Jeske, X Yuan, Q Fu, BA Bunnell… - Frontiers in …, 2021 - frontiersin.org
Human mesenchymal stem or stromal cells (hMSCs) are known for their potential in
regenerative medicine due to their differentiation abilities, secretion of trophic factors, and …

Micro‐fragmentation is a valid alternative to cell expansion and enzymatic digestion of adipose tissue for the treatment of knee osteoarthritis: a comparative preclinical …

G Filardo, M Tschon, F Perdisa… - Knee Surgery …, 2022 - Wiley Online Library
Purpose The aim of this study was to compare three procedures to exploit adipose‐derived
cells for the treatment of osteoarthritis (OA) in a preclinical model, to understand their …

Mesenchymal stem cells pretreated with collagen promote skin wound-healing

Z Kou, B Li, A Aierken, N Tan, C Li, M Han… - International Journal of …, 2023 - mdpi.com
The existing treatment modalities for skin injuries mainly include dressings, negative-
pressure wound treatment, autologous skin grafting, and high-pressure wound treatment. All …

Recombinant Klotho Protects Human Periodontal Ligament Stem Cells by Regulating Mitochondrial Function and the Antioxidant System during H2O2‐Induced …

H Chen, X Huang, C Fu, X Wu, Y Peng… - Oxidative medicine …, 2019 - Wiley Online Library
Human periodontal ligament stem cells (hPDLSCs) are a favourable source for tissue
engineering, but oxidative stress conditions during cell culture and transplantation could …

Clinical potential and current progress of mesenchymal stem cells for Parkinson's disease: a systematic review

Y Chen, J Shen, K Ke, X Gu - Neurological Sciences, 2020 - Springer
Parkinson's disease (PD) is the second most prevalent neurodegenerative disease
characterized by severe dyskinesia due to a progressive loss of dopaminergic neurons …