For several decades, dermatologists have utilized azathioprine to treat numerous
debilitating skin diseases. This synthetic purine analog is derived from 6-mercaptopurine. It …

Azathioprine and its metabolite 6-mercaptopurine (6-MP) are immunosuppressive drugs that
are used in organ transplantation and autoimmune and chronic inflammatory diseases such …

Azathioprine (AZA) is widely used in the management of rheumatological diseases. Despite
its efficacy, AZA can often cause bone marrow suppression, notably leucopenia, which has …

Background and aims: There are conflicting reports on the role of azathioprine (AZA)
thioguanine nucleotide (TGN) metabolites in optimising therapy for inflammatory bowel …

Nine polyketides, including two new benzophenone derivatives, peniphenone (1) and
methyl peniphenone (2), along with seven known xanthones (3–9) were obtained from …

For the intensive care professional who cares for abdominal organ transplant recipients, a
foundational knowledge of the core principles of immunosuppression management is …

Introduction: Inflammatory bowel disease is a chronic inflammation of the gut whose
pathogenesis is still unclear. Although no curative therapy is currently available, a number of …

The term Interactome describes the set of all molecular interactions in cells, especially in the
context of protein-protein interactions. These interactions are crucial for most cellular …

The discovery and implementation of thiopurine methyltransferase (TPMT)
pharmacogenetics has been a success story and has reduced the suffering from serious …

The electrochemical behavior and the interaction of the immunosuppressive drug
azathioprine (AZA) with deoxyribonucleic acid (DNA) were investigated using voltammetric …