The actin cytoskeleton response to oxidants: from small heat shock protein phosphorylation to changes in the redox state of actin itself
Actin is the major constituent of the cytoskeleton of almost all the eukaryotic cells. In vitro
experiments have indicated that oxidant-stressed nonmuscle mammalian cells undergo …
experiments have indicated that oxidant-stressed nonmuscle mammalian cells undergo …
Calcium ions and oxidative cell injury
S Orrenius, MJ Burkitt, GEN Kass… - Annals of Neurology …, 1992 - Wiley Online Library
Exposure of mammalian cells to oxidative stress induced by oxidation‐reduction‐active
quinones and other prooxidants results in depletion of intracellular glutathione, followed by …
quinones and other prooxidants results in depletion of intracellular glutathione, followed by …
Comparative effects of cadmium, copper, paraquat and benzo [a] pyrene on the actin cytoskeleton and production of reactive oxygen species (ROS) in mussel …
A Gómez-Mendikute, MP Cajaraville - Toxicology in vitro, 2003 - Elsevier
The immune defence of mussels is comprised of cell-mediated and humoral mechanisms, in
which haemocytes or blood cells play a key role. Environmental pollutants such as metallic …
which haemocytes or blood cells play a key role. Environmental pollutants such as metallic …
Disruption of podocyte cytoskeletal biomechanics by dasatinib leads to nephrotoxicity
RC Calizo, S Bhattacharya, JGC van Hasselt… - Nature …, 2019 - nature.com
Nephrotoxicity is a critical adverse event that leads to discontinuation of kinase inhibitor (KI)
treatment. Here we show, through meta-analyses of FDA Adverse Event Reporting System …
treatment. Here we show, through meta-analyses of FDA Adverse Event Reporting System …
The role of calcium in cell killing
P Nicotera, G Bellomo, S Orrenius - Chemical research in …, 1990 - ACS Publications
The involvement of Ca2+ in the regulation of a large number of physiological processes is
now well established. Along with this knowledge has come the understanding that Ca2+ can …
now well established. Along with this knowledge has come the understanding that Ca2+ can …
Cerebral vasospasm and free radicals
RL Macdonald, BK Weir - Free Radical Biology and Medicine, 1994 - Elsevier
The literature implicating free radical reactions in the genesis of cerebral vasospasm
following aneurysmal subarachnoid hemorrhage is reviewed. While this condition has …
following aneurysmal subarachnoid hemorrhage is reviewed. While this condition has …
Oxygen radicals production and actin filament disruption in bivalve haemocytes treated with benzo (a) pyrene
A Gómez-Mendikute, A Etxeberria, I Olabarrieta… - Marine Environmental …, 2002 - Elsevier
Haemocytes play an essential role in the internal defence of molluscs. It has been reported
that organic xenobiotics commonly found as pollutants in the marine environment impair …
that organic xenobiotics commonly found as pollutants in the marine environment impair …
Biotransformation and cytotoxicity of a brominated flame retardant, tetrabromobisphenol A, and its analogues in rat hepatocytes
Y Nakagawa, T Suzuki, H Ishii, A Ogata - Xenobiotica, 2007 - Taylor & Francis
The metabolism and cytotoxic effects of tetrabromobisphenol A (TBBPA), a phenolic flame
retardant, and its analogues were studied in freshly isolated rat hepatocytes and isolated …
retardant, and its analogues were studied in freshly isolated rat hepatocytes and isolated …
Cytotoxic effects of hydroxylated fullerenes on isolated rat hepatocytes via mitochondrial dysfunction
Y Nakagawa, T Suzuki, H Ishii, D Nakae, A Ogata - Archives of toxicology, 2011 - Springer
The cytotoxic effects of hydroxylated fullerenes, also termed fullerenols or fullerols [C 60
(OH) n], which are known nanomaterials and water-soluble fullerene derivatives, were …
(OH) n], which are known nanomaterials and water-soluble fullerene derivatives, were …
Cell damage and death by autoschizis in human bladder (RT4) carcinoma cells resulting from treatment with ascorbate and menadione
J Gilloteaux, JM Jamison, DR Neal… - Ultrastructural …, 2010 - Taylor & Francis
A human bladder carcinoma cell line RT4 was sham-treated with buffer or treated with
ascorbate (VC) alone, menadione alone (VK3), or a combination of ascorbate: menadione …
ascorbate (VC) alone, menadione alone (VK3), or a combination of ascorbate: menadione …