The evolutionary success of an organism is a testament to its inherent capacity to keep pace
with environmental conditions that change over short and long periods. Mechanisms …

Transcription is an essential step in gene expression and its understanding has been one of
the major interests in molecular and cellular biology. By precisely tuning gene expression …

RegulonDB, first published 20 years ago, is a comprehensive electronic resource about
regulation of transcription initiation of Escherichia coli K-12 with decades of knowledge from …

SUMMARY A major part of organismal complexity and versatility of prokaryotes resides in
their ability to fine-tune gene expression to adequately respond to internal and external …

Related organisms typically respond to a given cue by altering the level or activity of
orthologous transcription factors, which, paradoxically, often regulate expression of distinct …

Following recent discoveries of colocalization of downstream-regulating genes in living
cells, the impact of the spatial distance between such genes on the kinetics of gene product …

Gene regulation in bacteria is usually described as an adaptive response to an
environmental change so that genes are expressed when they are required. We instead …

Brucella abortus is a facultative intracellular pathogen causing a severe zoonotic disease
worldwide. The two-component regulatory system (TCS) BvrR/BvrS of B. abortus is …

To understand non-trivial biological functions, it is crucial to develop minimal synthetic
models that capture their basic features. Here, we demonstrate a sequence-independent …

Abstract Background The Bacillus cereus sensu lato group consists of six species (B.
anthracis, B. cereus, B. mycoides, B. pseudomycoides, B. thuringiensis, and B …