The last decade has been somewhat of a renaissance period for the field of macrophage
biology. This renewed interest, combined with the advent of new technologies and …

Inflammatory monocytes and tissue-resident macrophages are key regulators of tissue
repair, regeneration, and fibrosis. After tissue injury, monocytes and macrophages undergo …

During respiration, humans breathe in more than 10,000 liters of non-sterile air daily,
allowing some pathogens access to alveoli. Interestingly, alveoli outnumber alveolar …

Programs defining tissue-resident macrophage identity depend on local environmental
cues. For alveolar macrophages (AMs), these signals are provided by immune and …

Macrophages are essential innate immune cells found throughout the body that have
protective and pathogenic functions in many diseases. When activated, macrophages can …

Macrophages are critical for innate immune defense and also control organ homeostasis in
a tissue-specific manner. They provide a fitting model to study the impact of ontogeny and …

Macrophages have protective roles in immunity to pathogens, tissue development,
homeostasis and repair following damage. Maladaptive immunity and inflammation provoke …

Distinct macrophage populations throughout the body display highly heterogeneous
transcriptional and epigenetic programs. Recent research has highlighted that these profiles …

Macrophages are essential components of mammalian tissues. Although historically known
mainly for their function in host defense and the clearance of apoptotic cells, macrophages …

Macrophages are immune cells of haematopoietic origin that provide crucial innate immune
defence and have tissue-specific functions in the regulation and maintenance of organ …