Endoplasmic reticulum stress: molecular mechanism and therapeutic targets

X Chen, C Shi, M He, S Xiong, X Xia - Signal transduction and targeted …, 2023 - nature.com
The endoplasmic reticulum (ER) functions as a quality-control organelle for protein
homeostasis, or “proteostasis”. The protein quality control systems involve ER-associated …

Glaucoma in adults—screening, diagnosis, and management: a review

JD Stein, AP Khawaja, JS Weizer - Jama, 2021 - jamanetwork.com
Importance Glaucoma is the most common cause of irreversible blindness worldwide. Many
patients with glaucoma are asymptomatic early in the disease course. Primary care …

Primary open-angle glaucoma preferred practice pattern®

SJ Gedde, K Vinod, MM Wright, KW Muir, JT Lind… - Ophthalmology, 2021 - Elsevier
Background Primary open angle glaucoma (POAG) is a chronic, progressive ocular disease
causing loss of the optic nerve rim and retinal nerve fiber layer (RNFL) with associated …

The pathophysiology and treatment of glaucoma: a review

RN Weinreb, T Aung, FA Medeiros - Jama, 2014 - jamanetwork.com
Importance Glaucoma is a worldwide leading cause of irreversible vision loss. Because it
may be asymptomatic until a relatively late stage, diagnosis is frequently delayed. A general …

[PDF][PDF] Primary open-angle glaucoma preferred practice pattern® guidelines

BE Prum, LF Rosenberg, SJ Gedde, SL Mansberger… - …, 2016 - academia.edu
Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy in adults
in which there is a characteristic acquired atrophy of the optic nerve and loss of retinal …

[HTML][HTML] Prospective, randomized, controlled pivotal trial of an ab interno implanted trabecular micro-bypass in primary open-angle glaucoma and cataract: two-year …

TW Samuelson, SR Sarkisian Jr, DM Lubeck, MC Stiles… - Ophthalmology, 2019 - Elsevier
Purpose Evaluate the safety and effectiveness of an ab interno implanted (iStent inject)
Trabecular Micro-Bypass System (Glaukos Corporation, San Clemente, CA) in combination …

Glaucoma treatment trends: a review

R Conlon, H Saheb, IIK Ahmed - Canadian Journal of Ophthalmology, 2017 - Elsevier
Glaucoma is one of the most common causes of blindness worldwide, and its prevalence is
increasing. The aim of the present review is to describe the current medical and surgical …

Drug delivery to the anterior segment of the eye: A review of current and future treatment strategies

M Mofidfar, B Abdi, S Ahadian, E Mostafavi… - International journal of …, 2021 - Elsevier
Research in the development of ophthalmic drug formulations and innovative technologies
over the past few decades has been directed at improving the penetration of medications …

Comparative effectiveness of first-line medications for primary open-angle glaucoma: a systematic review and network meta-analysis

T Li, K Lindsley, B Rouse, H Hong, Q Shi, DS Friedman… - Ophthalmology, 2016 - Elsevier
Topic Primary open-angle glaucoma (POAG) is a highly prevalent condition worldwide and
the most common cause of irreversible sight loss. The objective is to assess the comparative …

Micropulse cyclophotocoagulation: initial results in refractory glaucoma

ME Emanuel, DS Grover, RL Fellman… - Journal of …, 2017 - journals.lww.com
Purpose: The purpose of this study is to evaluate the use of micropulse transscleral
cyclophotocoagulation (MP-TSCPC), a new and increasingly popular treatment, in patients …