The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

For more than two decades, HIV has infected millions of people worldwide each year
through mucosal transmission. Our knowledge of how HIV secures a foothold at both the …

DENDRITIC cells comprise a system of highly efficient antigen-presenting cells which initiate
immune responses such as the sensitization of T cells restricted by major histocompatibility …

Despite considerable advances in HIV science in the past 20 years, the reason why HIV-1
infection is pathogenic is still debated and the goal of eradicating HIV-1 infection remains …

Dendritic cells (DCs) play important roles in orchestrating host immunity against invading
pathogens, representing one of the first responders to infection by mucosal invaders. From …

Monocytes were maintained in tissue culture for greater than 3 mo in media supplemented
with rCSF-1. These cultures provided susceptible target cells for isolation and propagation of …

Contact between various epithelial cell lines and HIV chronically infected mononuclear cell
lines results in a massive and rapid budding of HIV virions toward the epithelium followed by …

Better understanding of the pathogenesis of acquired immunodeficiency syndrome (AIDS)
would be greatly facilitated by a relevant animal model that uses molecularly cloned virus of …

CELLS of the mononuclear phagocyte system are the predominant cell producing HIV-1 in
most tissues, including the central nervous system (CNS) 1–4, spinal cord5, lung6 and …

Understanding the mechanisms of HIV transmission to women will be crucial to the
development of effective strategies to curb this epidemic. Current data suggest that HIV has …