Introduction: This article is part of the Focus Theme of Methods of Information in Medicine on
the German Medical Informatics Initiative. Future medicine will be predictive, preventive …

Abstract Background Rare disease registries (RDRs) are valuable tools for improving
clinical care and advancing research. However, they often vary qualitatively, structurally, and …

Background The collection of data and biospecimens which characterize patients and
probands in-depth is a core element of modern biomedical research. Relevant data must be …

Within the scope of the two NUM projects CODEX and RACOON we developed a
preliminary technical concept for documenting clinical and radiological COVID-19 data in a …

Background Privacy must be protected when sensitive biomedical data is shared, eg for
research purposes. Data de-identification is an important safeguard, where datasets are …

Background: Pseudonymization has become a best practice to securely manage the
identities of patients and study participants in medical research projects and data sharing …

Background The SARS-CoV-2 pandemic has demonstrated once again that rapid
collaborative research is essential for the future of biomedicine. Large research networks …

Objectives Managing participants and their data are fundamental for the success of a clinical
trial. Our review identifies and describes processes that deal with management of trial …

Infectious complications are the major cause of morbidity and mortality after solid organ and
stem cell transplantation. To better understand host and environmental factors associated …

Background Individualization and patient-specific optimization of treatment is a major goal of
modern health care. One way to achieve this goal is the application of high-resolution …