[HTML][HTML] Advances in the pathogenesis of psoriasis: from keratinocyte perspective

X Zhou, Y Chen, L Cui, Y Shi, C Guo - Cell death & disease, 2022 - nature.com
Psoriasis is a complex long-lasting inflammatory skin disease with high prevalence and
associated comorbidity. It is characterized by epidermal hyperplasia and dermal infiltration …

Psoriasis: epidemiology, clinical features, and quality of life

RGB Langley, GG Krueger, CEM Griffiths - Annals of the rheumatic …, 2005 - ard.bmj.com
Psoriasis is a common chronic, recurrent, immune mediated disease of the skin and joints. It
can have a significant negative impact on the physical, emotional, and, psychosocial …

[HTML][HTML] A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes

M Cargill, SJ Schrodi, M Chang, VE Garcia… - The American Journal of …, 2007 - cell.com
We performed a multitiered, case-control association study of psoriasis in three independent
sample sets of white North American individuals (1,446 cases and 1,432 controls) with …

Genetic and epigenetic basis of psoriasis pathogenesis

A Chandra, A Ray, S Senapati, R Chatterjee - Molecular immunology, 2015 - Elsevier
Psoriasis is a chronic inflammatory skin disease whose prevalence varies among different
populations worldwide. It is a complex multi-factorial disease and the exact etiology is …

Genetic epidemiology of psoriasis and psoriatic arthritis

P Rahman, JT Elder - Annals of the rheumatic diseases, 2005 - ard.bmj.com
Psoriasis and psoriatic arthritis (PsA) are interrelated disorders, as most patients with PsA
also have psoriasis. Thus it is not surprising that epidemiological and immunogenetic …

The genetics of psoriasis, psoriatic arthritis and atopic dermatitis

AM Bowcock, WOCM Cookson - Human molecular genetics, 2004 - academic.oup.com
Psoriasis and atopic dermatitis are chronic and relapsing inflammatory diseases of the skin
associated with various immunologic abnormalities. Approximately 30% of psoriasis patients …

Insights into psoriasis and other inflammatory diseases from large-scale gene expression studies

AM Bowcock, W Shannon, F Du… - Human molecular …, 2001 - academic.oup.com
Approximately 2% of the Caucasian population is affected by psoriasis (PS); a chronic
inflammatory skin disease triggered by both genetic and environmental risk factors. In …

The genetics of psoriasis 2001: the odyssey continues

JT Elder, RP Nair, T Henseler, S Jenisch… - Archives of …, 2001 - jamanetwork.com
Accumulating evidence indicates that psoriasis is a multifactorial disorder caused by the
concerted action of multiple disease genes in a single individual, triggered by environmental …

[HTML][HTML] Searching for the major histocompatibility complex psoriasis susceptibility gene

F Capon, M Munro, R Trembath, J Barker - Journal of investigative …, 2002 - Elsevier
Psoriasis, a common skin disorder, is widely regarded to be multifactorial in origin including
gene-gene and gene-environment interactions. Genetic and allelic heterogeneity …

Association of interleukin‐23 receptor variants with ankylosing spondylitis

P Rahman, RD Inman, DD Gladman… - Arthritis & …, 2008 - Wiley Online Library
Objective Recent studies have shown that a nonsynonymous single‐nucleotide
polymorphism (SNP)(Arg381Gln; rs11209026) in the interleukin‐23 receptor (IL‐23R) gene …