Fabrication of functional scaffolds for tissue engineering and regenerative medicine
applications requires material systems with precise control over cellular performance. 3D …

Biophysical cues play a key role in directing the lineage commitment of mesenchymal stem
cells or multipotent stromal cells (MSC s), but the mechanotransductive mechanisms at play …

Fluid flow dynamics within porous scaffolds for tissue engineering play a critical role in the
transport of fundamental materials to the cells and in controlling the biocompatibility of the …

Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention
in the scientific world because of their differentiation potential into osteoblasts …

Certain polymeric materials such as polyurethanes (PUs) are the most prevalent class of
used biomaterials in regenerative medicine and have been widely explored as vascular …

Electrical stimulation (ES) is predominantly used as a physical therapy modality to promote
tissue healing and functional recovery. Research efforts in both laboratory and clinical …

Since their discovery in the late eighties, the role of Rho GTPases in the regulation of cell
migration has been extensively studied and has mainly focused on the hallmark family …

One of the major issues in tissue engineering is regulation of stem cell differentiation toward
specific lineages. Unlike biological and chemical signals, physical signals with adjustable …

Osteogenesis and adipogenesis of bone marrow mesenchymal stem cells (BMSCs) are
regarded as being of great importance in the regulation of bone remodeling. In this study, rat …

Mechanical cell stretching may be an attractive strategy for the tissue engineering of
mechanically functional tissues. It has been demonstrated that cell growth and differentiation …