Endothelial cells, forming a monolayer along blood vessels, intricately regulate vascular
hemostasis, inflammatory responses, and angiogenesis. A key determinant of these …

The binding promiscuity of proteins defines their ability to indiscriminately bind multiple
unrelated molecules. Binding promiscuity is implicated, at least in part, in the off-target …

Abstract Background Von Willebrand factor (VWF) is a multimeric plasma protein that
bridges the gap between vessel injury and platelet capture at high shear rates. Under high …

Background Laboratory resurrection of ancient coagulation factor (F) IX variants generated
through ancestral sequence reconstruction led to the discovery of a FIX variant, designated …

The utility of CRISPR-Cas9 to repair or reverse diseased states that arise from recent
genetic mutations in the human genome is now widely appreciated. The use of CRISPR to" …

Sažetak Uvod: Von Willebrandova bolest je najčešći nasljedni poremećaj zgrušavanja krvi
koji nastaje zbog kvantitativnih ili kvalitativnih poremećaja sinteze von Willebrandovog …

Over the course of several million years, animals have evolved to survive predation. The
development of boney jaws and the ability to bite coincided with the ability to withstand and …