The growth cone, which is a unique structure with high motility that forms at the tips of
extending axons and dendrites, is crucial to neuronal network formation. Axonal growth of …

The Wnt signaling pathway plays important roles during different stages of neuronal
development, including neuronal polarization and dendritic and axonal outgrowth. However …

During nervous system development, numerous cues within the extracellular matrix
microenvironment (ECM) guide the growing neurites along specific pathways to reach their …

Objective. Cochlear implants provide auditory perception to those with severe to profound
sensorineural hearing loss: however, the quality of sound perceived by users does not …

A stochastic model is proposed for the position of the tip of an axon. Parameters in the model
are determined from laboratory data. The first step is the reduction of inherent error in the …

The confined and crowded environment of developing brains imposes spatial constraints on
neuronal cells that have evolved individual and collective strategies to optimize their growth …

Myosin II (MII) activity is required for elongating mammalian sensory axons to change speed
and direction in response to Nerve Growth Factor (NGF) and laminin-1 (LN). NGF signaling …

In the field of image analysis, geometric modeling and simulation of real-world problems,
spline-based methods are powerful tools to develop smooth and accurate representation of …

Abstract As Tecnologias de Informação e Comunicação (TIC), omnipresentes nas
sociedades atuais, permitiram o alargamento dos contextos e momentos de aprendizagem …

In this work we propose a 2D discrete stochastic model for the simulation of axonal
biogenesis. The model is defined by a third order Markov Chain. The model considers two …