Mammalian MAPK signal transduction pathways activated by stress and inflammation: a 10-year update
JM Kyriakis, J Avruch - Physiological reviews, 2012 - journals.physiology.org
The mammalian stress-activated families of mitogen-activated protein kinases (MAPKs)
were first elucidated in 1994, and by 2001, substantial progress had been made in …
were first elucidated in 1994, and by 2001, substantial progress had been made in …
Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions
G Pearson, F Robinson, T Beers Gibson, B Xu… - Endocrine …, 2001 - academic.oup.com
Mitogen-activated protein (MAP) kinases comprise a family of ubiquitous proline-directed,
protein-serine/threonine kinases, which participate in signal transduction pathways that …
protein-serine/threonine kinases, which participate in signal transduction pathways that …
Tumor necrosis factor signaling
H Wajant, K Pfizenmaier, P Scheurich - Cell Death & Differentiation, 2003 - nature.com
A single mouse click on the topic tumor necrosis factor (TNF) in PubMed reveals about 50
000 articles providing one or the other information about this pleiotropic cytokine or its …
000 articles providing one or the other information about this pleiotropic cytokine or its …
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
JM Kyriakis, J Avruch - Physiological reviews, 2001 - journals.physiology.org
The molecular details of mammalian stress-activated signal transduction pathways have
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
only begun to be dissected. This, despite the fact that the impact of these pathways on the …
MAP kinases
Z Chen, TB Gibson, F Robinson, L Silvestro… - Chemical …, 2001 - ACS Publications
MAP Kinases | Chemical Reviews ACS ACS Publications C&EN CAS Find my institution Log In
Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most Read Quick View Share …
Chemical Reviews ACS Publications. Most Trusted. Most Cited. Most Read Quick View Share …
The Ste20 group kinases as regulators of MAP kinase cascades
I Dan, NM Watanabe, A Kusumi - Trends in cell biology, 2001 - cell.com
Abstract Ste20p (sterile 20 protein) is a putative yeast mitogen-activated protein kinase
kinase kinase kinase (MAP4K) involved in the mating pathway. Its homologs in mammals …
kinase kinase kinase (MAP4K) involved in the mating pathway. Its homologs in mammals …
[HTML][HTML] A small molecule screen in stem-cell-derived motor neurons identifies a kinase inhibitor as a candidate therapeutic for ALS
YM Yang, SK Gupta, KJ Kim, BE Powers, A Cerqueira… - Cell stem cell, 2013 - cell.com
Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease,
characterized by motor neuron (MN) death, for which there are no truly effective treatments …
characterized by motor neuron (MN) death, for which there are no truly effective treatments …
Matrix metalloproteinases in wound repair
L Ravanti, VM Kähäri - International journal of …, 2000 - spandidos-publications.com
Wound repair is initiated with the aggregation of platelets, formation of a fibrin clot, and
release of growth factors from the activated coagulation pathways, injured cells, platelets …
release of growth factors from the activated coagulation pathways, injured cells, platelets …
The ERK cascade: a prototype of MAPK signaling
H Rubinfeld, R Seger - Molecular biotechnology, 2005 - Springer
Sequential activation of protein kinases within the mitogen-activated protein kinase (MAPK)
cascades is a common mechanism of signal transduction in many cellular processes. Four …
cascades is a common mechanism of signal transduction in many cellular processes. Four …
[HTML][HTML] The N-CoR-HDAC3 nuclear receptor corepressor complex inhibits the JNK pathway through the integral subunit GPS2
The corepressors N-CoR and SMRT partner with histone deacetylases (HDACs) in diverse
repression pathways. We report here that GPS2, a protein involved in intracellular signaling …
repression pathways. We report here that GPS2, a protein involved in intracellular signaling …