Oxidative stress and inflammation have been recognized as important contributors to the risk
of chronic non-communicable diseases. Polyunsaturated fatty acids (PUFAs) may regulate …

Introduction: There has long been an interest in the effects of diet on mental health, and the
interaction of the two with stress; however, the nature of these relationships is not well …

Objectives The therapeutic use of nutrient-based 'nutraceuticals' and plant-based
'phytoceuticals' for the treatment of mental disorders is common; however, despite recent …

We conducted this meta-analysis of double-blind randomized placebo-controlled trials to
estimate the efficacy of omega-3 polyunsaturated fatty acids (PUFAs), especially …

Background: The role of fat consumption in human health has been the subject of much
debate and research. While the association between fat intake and cardiovascular health …

Classically, polyunsaturated fatty acids (PUFA) were largely thought to be relatively inert
structural components of brain, largely important for the formation of cellular membranes …

Background: Studies investigating the impact of a variety of inflammatory stimuli on the brain
and behavior have reported evidence that inflammation and release of inflammatory …

EPA and DHA appear to be the most important n-3 fatty acids, but roles for n-3
docosapentaenoic acid are now also emerging. Intakes of EPA and DHA are usually low …

Abstract Recently, omega-3 long-chain polyunsaturated fatty acids (n-3 LC-PUFAs) have
gained substantial interest due to their specific structure and biological functions. Humans …

Notwithstanding advances in understanding the pathophysiology of major depressive
disorder (MDD), no single mechanism can explain all facets of this disorder. An expanding …