Major depressive disorder (MDD) is a psychiatric disease of still poorly understood
molecular etiology. Extensive studies at different molecular levels point to a high complexity …

As clinicians delivering health care, we are very good at treating disease but often not as
good at treating the person. The focus of our attention has been on the specific physical …

Major depressive disorder is the most common neuropsychiatric disorder, affecting 11% of
veterans. Here we report results of a large meta-analysis of depression using data from the …

Mental health problems are associated with lower quality of life, increased unscheduled
care, high economic and social cost, and increased mortality. Nature-based interventions …

Background The inflammation and oxidative stress (OS) have been considered crucial
components of the pathogenesis of depression. Edaravone (EDA), a free radical scavenger …

Objective: Estimates of prevalence and burden of treatment-resistant depression (TRD) vary
widely in the literature. This study evaluated the prevalence and burden of TRD and the …

Depression represents the number one cause of disability worldwide and is often fatal.
Inflammatory processes have been implicated in the pathophysiology of depression. It is …

Background Homelessness continues to be a pressing public health concern in many
countries, and mental disorders in homeless persons contribute to their high rates of …

Importance Major depressive disorder (MDD) is a substantial public health burden, but
current treatments have limited effectiveness and adherence. Recent evidence suggests that …

Women are at twice the risk for anxiety and depression disorders as men are, although the
underlying biological factors and mechanisms are largely unknown. In this review, we …