Mitochondrial dysfunction plays central role in nonalcoholic fatty liver disease

R Ramanathan, AH Ali, JA Ibdah - International Journal of Molecular …, 2022 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is a global pandemic that affects one-quarter of the
world's population. NAFLD includes a spectrum of progressive liver disease from steatosis to …

Nonalcoholic fatty liver disease (NAFLD). Mitochondria as players and targets of therapies?

A Di Ciaula, S Passarella, H Shanmugam… - International Journal of …, 2021 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease and
represents the hepatic expression of several metabolic abnormalities of high epidemiologic …

Natural polysaccharides protect against diet-induced obesity by improving lipid metabolism and regulating the immune system

C Tang, Y Wang, D Chen, M Zhang, J Xu, C Xu… - Food Research …, 2023 - Elsevier
Unhealthy dietary patterns-induced obesity and obesity-related complications pose a great
threat to human health all over the world. Accumulating evidence suggests that the …

Mitochondrial metabolic dysfunction and non-alcoholic fatty liver disease: new insights from pathogenic mechanisms to clinically targeted therapy

Y Zheng, S Wang, J Wu, Y Wang - Journal of Translational Medicine, 2023 - Springer
Metabolic dysfunction-associated fatty liver disease (MAFLD) is among the most widespread
metabolic disease globally, and its associated complications including insulin resistance …

Friend or foe: lipid droplets as organelles for protein and lipid storage in cellular stress response, aging and disease

F Geltinger, L Schartel, M Wiederstein, J Tevini… - Molecules, 2020 - mdpi.com
Lipid droplets (LDs) were considered as a mere lipid storage organelle for a long time.
Recent evidence suggests that LDs are in fact distinct and dynamic organelles with a …

Altered mitochondrial quality control in rats with metabolic dysfunction-associated fatty liver disease (MAFLD) induced by high-fat feeding

F Cioffi, A Giacco, G Petito, R de Matteis, R Senese… - Genes, 2022 - mdpi.com
Metabolic dysfunction-associated fatty liver disease (MAFLD) is defined as the presence of
hepatic steatosis in addition to one of three metabolic conditions: overweight/obesity, type 2 …

Quercetin and non-alcoholic fatty liver disease: A review based on experimental data and bioinformatic analysis

L Chen, J Liu, G Mei, H Chen, S Peng, Y Zhao… - Food and Chemical …, 2021 - Elsevier
Quercetin, a polyphenol widely present in the plant kingdom, has received great interest due
to pleiotropic effects. As evidenced by animal and cellular studies, quercetin exerts …

Thyroid hormone and mitochondrial dysfunction: therapeutic implications for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

R Ramanathan, SA Patwa, AH Ali, JA Ibdah - Cells, 2023 - mdpi.com
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly termed
nonalcoholic fatty liver disease (NAFLD), is a widespread global health concern that affects …

Steatosis induced by nonylphenol in HepG2 cells and the intervention effect of curcumin

D Shan, J Wang, Q Di, Q Jiang, Q Xu - Food & Function, 2022 - pubs.rsc.org
Non-alcoholic fatty liver disease (NAFLD) has increasingly become a serious public health
problem. There is growing evidence that nonylphenol (NP) exposure may cause steatosis …

[HTML][HTML] Mitochondrial quality control: its role in metabolic dysfunction-associated steatotic liver disease (MASLD)

S Shin, J Kim, JY Lee, J Kim, CM Oh - Journal of Obesity & …, 2023 - ncbi.nlm.nih.gov
Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly known as non-
alcoholic fatty liver disease, is characterized by hepatic steatosis and metabolic dysfunction …