Importance of the field: Vascular delivery of several classes of therapeutic agents may
benefit from carriage by red blood cells (RBC), for example, drugs that require delivery into …

Drug delivery has been greatly improved over the years by means of chemical and physical
agents that increase bioavailability, improve pharmacokinetic and reduce toxicities. At the …

Erythrocytes are potential biocompatible vectors for different bioactive substances, including
drugs. These can be used successfully as biological carriers of drugs, enzymes and …

Carrier erythrocytes, resealed erythrocytes loaded by a drug or other therapeutic agents,
have been exploited extensively in recent years for both temporally and spatially controlled …

Cells of macrophage lineage represent a key target of human immunodeficiency virus (HIV)
in addition to CD4-lymphocytes. The absolute number of infected macrophages in the body …

Multidisciplinary research efforts in the field of drug delivery have led to the development of
a variety of drug delivery systems (DDS) designed for site-specific delivery of diagnostic and …

The use of a physiological carrier to deliver therapeutics throughout the body to both
improve their efficacy while minimising inevitable adverse side effects, is an extremely …

Red blood cells (RBCs), or erythrocytes, have been promising endogenous candidates for
drug delivery for more than four decades. Armed with a better understanding of the diverse …

Red blood cells (RBC) are actually exploited as innovative drug delivery systems with
unconventional and convenient properties. Because of a long in vivo survival and a non …

Recently optimized technologies that permit the reversible opening of nanopores across the
red blood cell membrane, give the extraordinary opportunity for reengineering human …