miRNAs orchestration of gallbladder cancer-Particular emphasis on diagnosis, progression and drug resistance

RK Shahin, MA Elkady, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Gallbladder cancer (GBC) is characterized by a highly invasive nature and a poor prognosis,
with adenocarcinoma being the main histological subtype. According to statistical data …

HOTAIR LncRNA: a novel oncogenic propellant in human cancer

T Rajagopal, S Talluri, RL Akshaya, NR Dunna - Clinica chimica acta, 2020 - Elsevier
Long non-coding RNAs (lncRNAs) are an important novel class of non-coding RNAs having
lengths of 200 nucleotides and low expression. The HOX Transcript Antisense Intergenic …

Autophagy-related microRNAs: possible regulatory roles and therapeutic potential in and gastrointestinal cancers

MH Pourhanifeh, M Vosough… - Pharmacological …, 2020 - Elsevier
Gastrointestinal (GI) cancers with a high incidence rate and adverse complications are
associated with severe morbidity and mortality around the world. It is well recognized that …

MicroRNA-30a-5p inhibits gallbladder cancer cell proliferation, migration and metastasis by targeting E2F7

YY Ye, JW Mei, SS Xiang, HF Li, Q Ma, XL Song… - Cell Death & …, 2018 - nature.com
Gallbladder carcinoma (GBC), the most common malignant tumour of the bile duct, is highly
aggressive and has a poor prognosis. MicroRNA-30a-5p (miR-30a-5p) is an important …

Molecular pathogenesis of gallbladder cancer: An update

SK Mishra, N Kumari, N Krishnani - Mutation Research/Fundamental and …, 2019 - Elsevier
Gallbladder carcinoma (GBC) is the most aggressive gastrointestinal malignancy throughout
the world, with wide geographical variance. It is the subtype of biliary tract malignancy that …

[HTML][HTML] MiR-143-5p deficiency triggers EMT and metastasis by targeting HIF-1α in gallbladder cancer

M He, M Zhan, W Chen, S Xu, M Long… - Cellular Physiology and …, 2017 - karger.com
Background/Aims: Early metastasis plays a pivotal role in tumor-caused death in gallbladder
cancer (GBC) patients. Increasing evidence suggest that miR-143-5p is an active player …

Overexpression of microRNA-205-5p exerts suppressive effects on stem cell drug resistance in gallbladder cancer by down-regulating PRKCE

GF Zhang, JC Wu, HY Wang, WD Jiang… - Bioscience …, 2020 - portlandpress.com
Some microRNAs (miRs or miRNAs) have been reported to function as tumor suppressors in
gallbladder cancer (GBC). However, the specific effect of miR-205-5p on GBC remains …

miR-135b reverses chemoresistance of non-small cell lung cancer cells by downregulation of FZD1

W Su, Y Mo, F Wu, K Guo, J Li, Y Luo, H Ye… - Biomedicine & …, 2016 - Elsevier
Background Non-small cell lung cancer (NSCLC) chemoresistance usually limits the clinical
efficacy of chemotherapeutic approaches. However, few reports have revealed the …

SOI-nanowire biosensor for the detection of glioma-associated miRNAs in plasma

KA Malsagova, TO Pleshakova, RA Galiullin, AF Kozlov… - Chemosensors, 2020 - mdpi.com
Herein, we report the development of a highly sensitive nanotechnology-based system—
silicon-on-insulator nanowire biosensor for the revelation of microRNAs (miRNAs) …

A systemic review on the regulatory roles of miR-34a in gastrointestinal cancer

J Kong, W Wang - OncoTargets and therapy, 2020 - Taylor & Francis
MicroRNAs (miRNAs) are a class of endogenous non-coding single-stranded small-
molecule RNAs that regulate gene expression by repressing target messenger RNA …