Signal transducer and activator of transcription (STAT) 3 is one of the most complex
regulators of transcription. Constitutive activation of STAT3 has been reported in many types …

Signal transducer and activator of transcription 3 (STAT3) is a cytoplasmic transcription
factor that regulates cell proliferation, differentiation, apoptosis, angiogenesis, inflammation …

Signal transducer and activator of transcription 3 (STAT3) is a transcription factor that
regulates the expression of genes related to cell cycle, cell survival, and immune response …

Signal transducer and activator of transcription (STAT) proteins are latent transcription
factors that reside in the cytoplasm of several types of cells. In canonical signaling, upon …

Signal Transducers and Activators of Transcription (STATs) are a family of transcription
factors that regulate cell proliferation, differentiation, apoptosis, immune and inflammatory …

Oximes have been studied for decades because of their significant roles as
acetylcholinesterase reactivators. Over the last twenty years, a large number of oximes have …

Accumulating evidence has shown that Signal Transducer and Activator of Transcription 3
(STAT3) is thought to be a promising target for cancer therapy as STAT3 is frequently …

Epithelial ovarian cancer (EOC) is the most lethal of all gynecologic malignancies. Despite
advances in surgical and chemotherapeutic options, most patients with advanced EOC have …

STATs constitute a large family of transcription activators and transducers of signals that
have an important role in many cell functions as regulation of proliferation and differentiation …

Janus kinases (JAKs) are the non-receptor tyrosine kinases covering JAK1, JAK2, JAK3,
and TYK2 which regulate signal transductions of hematopoietic cytokines and growth factors …