The transcription factor NF-κB is a central mediator of inflammation with multiple links to
thrombotic processes. In this review, we focus on the role of NF-κB signaling in cell types …

Besides its important role in embryonic development and homeostatic self-renewal in adult
tissues, Wnt/β-catenin signaling exerts both anti-inflammatory and proinflammatory …

Hepatocellular carcinoma (HCC) is the second-leading cause of cancer-related death
worldwide and the factors influencing HCC progression are poorly understood. Here we …

Radiation therapy induces DNA damage and inflammation leading to fibrosis. Fibrosis can
occur 4 to 12 months after radiation therapy. This process worsens with time and years …

Although systemic or local inflammation, commonly featured by cytokine activation, is
implicated in patients with bone loss, the underlying mechanisms are still elusive. As …

In physiology conditions, the crosstalk of signaling pathways has been considered to extend
the functions of individual pathways and results in a more complex regulatory network. The …

Osteoarthritis (OA) is a common degenerative joint disease, which is closely related to
cartilage degradation. Anthocyanins, a natural flavonoid pigments, exhibit strong antioxidant …

Cross-regulation between the Wnt and nuclear factor (NF)-κB signaling pathways has
emerged as an important area for the regulation of a diverse array of genes and pathways …

Osteoarthritis (OA) is a joint disease that causes great pain to patients and imposes a
tremendous burden on the world's medical resources. Regulatory noncoding RNAs …

Multiple sclerosis (MS) is marked by neuroinflammation and demyelination with loss of
oligodendrocytes in the central nervous system. The immune response is regulated by …