Bone morphogenetic proteins: new insights into their roles and mechanisms in CNS development, pathology and repair
CG Hart, S Karimi-Abdolrezaee - Experimental Neurology, 2020 - Elsevier
Bone morphogenetic proteins (BMPs) are a highly conserved and diverse family of proteins
that play essential roles in various stages of development including the formation and …
that play essential roles in various stages of development including the formation and …
The context-dependent, combinatorial logic of BMP signaling
Cell-cell communication systems typically comprise families of ligand and receptor variants
that function together in combinations. Pathway activation depends on the complex way in …
that function together in combinations. Pathway activation depends on the complex way in …
Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals
M Manuel, KB Tan, Z Kozic, M Molinek, TS Marcos… - PLoS …, 2022 - journals.plos.org
The development of stable specialized cell types in multicellular organisms relies on
mechanisms controlling inductive intercellular signals and the competence of cells to …
mechanisms controlling inductive intercellular signals and the competence of cells to …
BMP2 inhibits cell proliferation by downregulating EZH2 in gastric cancer
Z Chen, L Yuan, X Li, J Yu, Z Xu - Cell Cycle, 2022 - Taylor & Francis
Gastric cancer is among the most common gastrointestinal malignancies. Recent studies
have suggested that bone morphogenetic protein-2 (BMP2) is related to the development …
have suggested that bone morphogenetic protein-2 (BMP2) is related to the development …
Zika virus E protein alters the properties of human fetal neural stem cells by modulating microRNA circuitry
Zika virus (ZV) infects neural stem cells (NSCs) and causes quiescence in NSCs, reducing
the pool of brain cells, leading to microcephaly. Despite conscientious efforts, the molecular …
the pool of brain cells, leading to microcephaly. Despite conscientious efforts, the molecular …
Bone Morphogenic Proteins in Pediatric Diffuse Midline Gliomas: How to Make New Out of Old?
C Berthelot, P Huchedé, A Bertrand-Chapel… - International Journal of …, 2024 - mdpi.com
The BMP pathway is one of the major signaling pathways in embryonic development,
ontogeny and homeostasis, identified many years ago by pioneers in developmental …
ontogeny and homeostasis, identified many years ago by pioneers in developmental …
BMPR-2 gates activity-dependent stabilization of primary dendrites during mitral cell remodeling
S Aihara, S Fujimoto, R Sakaguchi, T Imai - Cell reports, 2021 - cell.com
Developing neurons initially form excessive neurites and then remodel them based on
molecular cues and neuronal activity. Developing mitral cells in the olfactory bulb initially …
molecular cues and neuronal activity. Developing mitral cells in the olfactory bulb initially …
Cell-type-specific gene expression in developing mouse neocortex: intermediate progenitors implicated in axon development
Cerebral cortex projection neurons (PNs) are generated from intermediate progenitors (IPs),
which are in turn derived from radial glial progenitors (RGPs). To investigate developmental …
which are in turn derived from radial glial progenitors (RGPs). To investigate developmental …
Variation of human neural stem cells generating organizer states in vitro before committing to cortical excitatory or inhibitory neuronal fates
Better understanding of the progression of neural stem cells (NSCs) in the developing
cerebral cortex is important for modeling neurogenesis and defining the pathogenesis of …
cerebral cortex is important for modeling neurogenesis and defining the pathogenesis of …
The MuSK-BMP pathway maintains myofiber size in slow muscle through regulation of Akt-mTOR signaling
D Jaime, LA Fish, LA Madigan, C Xi, G Piccoli… - Skeletal Muscle, 2024 - Springer
Myofiber size regulation is critical in health, disease, and aging. MuSK (muscle-specific
kinase) is a BMP (bone morphogenetic protein) co-receptor that promotes and shapes BMP …
kinase) is a BMP (bone morphogenetic protein) co-receptor that promotes and shapes BMP …