Bone morphogenetic proteins (BMPs) are a highly conserved and diverse family of proteins
that play essential roles in various stages of development including the formation and …

Cell-cell communication systems typically comprise families of ligand and receptor variants
that function together in combinations. Pathway activation depends on the complex way in …

The development of stable specialized cell types in multicellular organisms relies on
mechanisms controlling inductive intercellular signals and the competence of cells to …

Gastric cancer is among the most common gastrointestinal malignancies. Recent studies
have suggested that bone morphogenetic protein-2 (BMP2) is related to the development …

Zika virus (ZV) infects neural stem cells (NSCs) and causes quiescence in NSCs, reducing
the pool of brain cells, leading to microcephaly. Despite conscientious efforts, the molecular …

The BMP pathway is one of the major signaling pathways in embryonic development,
ontogeny and homeostasis, identified many years ago by pioneers in developmental …

Developing neurons initially form excessive neurites and then remodel them based on
molecular cues and neuronal activity. Developing mitral cells in the olfactory bulb initially …

Cerebral cortex projection neurons (PNs) are generated from intermediate progenitors (IPs),
which are in turn derived from radial glial progenitors (RGPs). To investigate developmental …

Better understanding of the progression of neural stem cells (NSCs) in the developing
cerebral cortex is important for modeling neurogenesis and defining the pathogenesis of …

Myofiber size regulation is critical in health, disease, and aging. MuSK (muscle-specific
kinase) is a BMP (bone morphogenetic protein) co-receptor that promotes and shapes BMP …