As the prevalence of obesity continues to rise, the world is facing a major public health
concern. Obesity is a complex disease associated with an increase in several inflammatory …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

Vitamin D deficiency has been linked to the onset of diabetes. This review summarizes the
role of Vitamin D in maintaining the normal release of insulin by the pancreatic beta cells (β …

The host-seeking activity of hematophagous arthropods is essential for arboviral
transmission. Here, we demonstrate that mosquito-transmitted flaviviruses can manipulate …

From a biological point of view, aging can be considered a progressive inability of an
organism to react to stress, maintain homeostasis, and survive unfavourable changes during …

Adipose tissue is a complex, essential, and highly active metabolic and endocrine organ.
Besides adipocytes, adipose tissue contains connective tissue matrix, nerve tissue …

Obesity is one of the main risk factors for type 2 diabetes mellitus (T2DM). It is closely related
to metabolic disturbances in the adipose tissue that primarily functions as a fat reservoir. For …

Obesity and the related disorders of dyslipidemia and diabetes (components of syndrome X)
have become global health epidemics. Over the past decade, the elucidation of key …

Over the past two decades our view of adipose tissue has undergone a dramatic change
from an inert energy storage tissue to an active endocrine organ. Adipose tissue …

Obesity is associated with an array of health problems in adult and pediatric populations.
Understanding the pathogenesis of obesity and its metabolic sequelae has advanced …