Using mass spectrometry to identify ubiquitin and ubiquitin‐like protein conjugation sites

SM Jeram, T Srikumar, PGA Pedrioli, B Raught - Proteomics, 2009 - Wiley Online Library
Ubiquitin (Ub) and the ubiquitin‐like proteins (Ubls) are polypeptides that are covalently
conjugated to proteins and other biomolecules to modulate their turnover rate, localization …

Diagnostic and Therapeutic Application of Proteomics in Infectious Disease

FB Yihunie, MA Belete, G Fentahun… - Advances in Cell …, 2023 - Wiley Online Library
The study of an organism's genome, often known as “genomics,” has advanced quickly,
producing a wealth of publicly accessible genetic data. Despite how valuable the genome is; …

Plasmodium falciparum proteome changes in response to doxycycline treatment

S Briolant, L Almeras, M Belghazi… - Malaria journal, 2010 - Springer
Abstract Background The emergence of Plasmodium falciparum resistance to most anti-
malarial compounds has highlighted the urgency to develop new drugs and to clarify the …

Large-Scale Differential Proteome Analysis in Plasmodium falciparum under Drug Treatment

JH Prieto, S Koncarevic, SK Park, J Yates III, K Becker - PLoS One, 2008 - journals.plos.org
Proteome studies contribute markedly to our understanding of parasite biology, host-
parasite interactions, and mechanisms of drug action. For most antimalarial drugs neither …

Quantitative mass spectrometric analysis of autoantibodies as a paradigm shift in autoimmune serology

AYS Lee, T Chataway, AD Colella, TP Gordon… - Frontiers in …, 2019 - frontiersin.org
Affecting∼ 7–9% of individuals worldwide (1), autoimmunity is a relatively common
condition that can cause substantial morbidity and mortality (2). However, there are …

Proteomic analysis of PBMCs: characterization of potential HIV-associated proteins

L Zhang, X Jia, X Zhang, J Sun, X Peng, T Qi, F Ma… - Proteome science, 2010 - Springer
Background The human immunodeficiency virus type 1 (HIV-1) pandemic has continued
unabated for nearly 30 years. To better understand the influence of virus on host cells, we …

Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock

A Ruiz-Sanmartín, V Ribas, D Suñol… - Plos one, 2022 - journals.plos.org
Introduction The search for new biomarkers that allow an early diagnosis in sepsis and
predict its evolution has become a necessity in medicine. The objective of this study is to …

Mass spectrometry-based bacterial proteomics: focus on dermatologic microbial pathogens

Y Soufi, B Soufi - Frontiers in microbiology, 2016 - frontiersin.org
The composition of human skin acts as a natural habitat for various bacterial species that
function in a commensal and symbiotic fashion. In a healthy individual, bacterial flora serves …

High throughput proteomic analysis and a comparative review identify the nuclear chaperone, Nucleophosmin among the common set of proteins modulated in …

R Abraham, P Mudaliar, A Jaleel, J Srikanth… - Journal of …, 2015 - Elsevier
Global re-emergence of Chikungunya virus (CHIKV) has renewed the interest in its cellular
pathogenesis. We subjected CHIKV-infected Human Embryo Kidney cells (HEK293), a …

Unique and differential protein signatures within the mononuclear cells of HIV-1 and HCV mono-infected and co-infected patients

NM Boukli, V Shetty, L Cubano, M Ricaurte… - Clinical proteomics, 2012 - Springer
Background Pathogenesis of liver damage in patients with HIV and HCV co-infection is
complex and multifactorial. Although global awareness regarding HIV-1/HCV co-infection is …