Using mass spectrometry to identify ubiquitin and ubiquitin‐like protein conjugation sites
Ubiquitin (Ub) and the ubiquitin‐like proteins (Ubls) are polypeptides that are covalently
conjugated to proteins and other biomolecules to modulate their turnover rate, localization …
conjugated to proteins and other biomolecules to modulate their turnover rate, localization …
Diagnostic and Therapeutic Application of Proteomics in Infectious Disease
FB Yihunie, MA Belete, G Fentahun… - Advances in Cell …, 2023 - Wiley Online Library
The study of an organism's genome, often known as “genomics,” has advanced quickly,
producing a wealth of publicly accessible genetic data. Despite how valuable the genome is; …
producing a wealth of publicly accessible genetic data. Despite how valuable the genome is; …
Plasmodium falciparum proteome changes in response to doxycycline treatment
S Briolant, L Almeras, M Belghazi… - Malaria journal, 2010 - Springer
Abstract Background The emergence of Plasmodium falciparum resistance to most anti-
malarial compounds has highlighted the urgency to develop new drugs and to clarify the …
malarial compounds has highlighted the urgency to develop new drugs and to clarify the …
Large-Scale Differential Proteome Analysis in Plasmodium falciparum under Drug Treatment
Proteome studies contribute markedly to our understanding of parasite biology, host-
parasite interactions, and mechanisms of drug action. For most antimalarial drugs neither …
parasite interactions, and mechanisms of drug action. For most antimalarial drugs neither …
Quantitative mass spectrometric analysis of autoantibodies as a paradigm shift in autoimmune serology
AYS Lee, T Chataway, AD Colella, TP Gordon… - Frontiers in …, 2019 - frontiersin.org
Affecting∼ 7–9% of individuals worldwide (1), autoimmunity is a relatively common
condition that can cause substantial morbidity and mortality (2). However, there are …
condition that can cause substantial morbidity and mortality (2). However, there are …
Proteomic analysis of PBMCs: characterization of potential HIV-associated proteins
L Zhang, X Jia, X Zhang, J Sun, X Peng, T Qi, F Ma… - Proteome science, 2010 - Springer
Background The human immunodeficiency virus type 1 (HIV-1) pandemic has continued
unabated for nearly 30 years. To better understand the influence of virus on host cells, we …
unabated for nearly 30 years. To better understand the influence of virus on host cells, we …
Characterization of a proteomic profile associated with organ dysfunction and mortality of sepsis and septic shock
A Ruiz-Sanmartín, V Ribas, D Suñol… - Plos one, 2022 - journals.plos.org
Introduction The search for new biomarkers that allow an early diagnosis in sepsis and
predict its evolution has become a necessity in medicine. The objective of this study is to …
predict its evolution has become a necessity in medicine. The objective of this study is to …
Mass spectrometry-based bacterial proteomics: focus on dermatologic microbial pathogens
Y Soufi, B Soufi - Frontiers in microbiology, 2016 - frontiersin.org
The composition of human skin acts as a natural habitat for various bacterial species that
function in a commensal and symbiotic fashion. In a healthy individual, bacterial flora serves …
function in a commensal and symbiotic fashion. In a healthy individual, bacterial flora serves …
High throughput proteomic analysis and a comparative review identify the nuclear chaperone, Nucleophosmin among the common set of proteins modulated in …
Global re-emergence of Chikungunya virus (CHIKV) has renewed the interest in its cellular
pathogenesis. We subjected CHIKV-infected Human Embryo Kidney cells (HEK293), a …
pathogenesis. We subjected CHIKV-infected Human Embryo Kidney cells (HEK293), a …
Unique and differential protein signatures within the mononuclear cells of HIV-1 and HCV mono-infected and co-infected patients
NM Boukli, V Shetty, L Cubano, M Ricaurte… - Clinical proteomics, 2012 - Springer
Background Pathogenesis of liver damage in patients with HIV and HCV co-infection is
complex and multifactorial. Although global awareness regarding HIV-1/HCV co-infection is …
complex and multifactorial. Although global awareness regarding HIV-1/HCV co-infection is …