Papillomavirus infections—a major cause of human cancers
H Zur Hausen - Biochimica et biophysica acta (BBA)-reviews on cancer, 1996 - Elsevier
The papillomavirus family represents a remarkably heterogeneous group of viruses. At
present, 77 distinct genotypes have been identified in humans and partial sequences have …
present, 77 distinct genotypes have been identified in humans and partial sequences have …
[HTML][HTML] Papillomavirus genome structure, expression, and post-transcriptional regulation
ZM Zheng, CC Baker - Frontiers in bioscience: a journal and virtual …, 2006 - ncbi.nlm.nih.gov
Papillomaviruses are a group of small non-enveloped DNA tumor viruses whose infection
usually causes benign epithelial lesions (warts). Certain types of HPVs, such as HPV-16 …
usually causes benign epithelial lesions (warts). Certain types of HPVs, such as HPV-16 …
[HTML][HTML] The E4 protein; structure, function and patterns of expression
J Doorbar - Virology, 2013 - Elsevier
The papillomavirus E4 open reading frame (ORF) is contained within the E2 ORF, with the
primary E4 gene-product (E1∧ E4) being translated from a spliced mRNA that includes the …
primary E4 gene-product (E1∧ E4) being translated from a spliced mRNA that includes the …
The not-so-good, the bad and the ugly: HPV E5, E6 and E7 oncoproteins in the orchestration of carcinogenesis
O Basukala, L Banks - Viruses, 2021 - mdpi.com
Infection with HPV starts with the access of the viral particles to basal cells in the epidermis,
potentially via microtraumas to the skin. The basal cells are able to keep away these …
potentially via microtraumas to the skin. The basal cells are able to keep away these …
Expression of vaccinia recombinant HPV 16 L1 and L2 ORF proteins in epithelial cells is sufficient for assembly of HPV virion-like particles
J Zhou, XY Sun, DJ Stenzel, IH Frazer - Virology, 1991 - Elsevier
A recombinant vaccinia virus termed pLC201 VV was designed to coexpress the Li and L2
late genes of human papillomavirus type 16 (HPV16). Synthesis of the Li and L2 proteins …
late genes of human papillomavirus type 16 (HPV16). Synthesis of the Li and L2 proteins …
HPV16 and HPV18 genome structure, expression, and post-transcriptional regulation
L Yu, V Majerciak, ZM Zheng - International journal of molecular sciences, 2022 - mdpi.com
Human papillomaviruses (HPV) are a group of small non-enveloped DNA viruses whose
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …
infection causes benign tumors or cancers. HPV16 and HPV18, the two most common high …
The role of the E6-p53 interaction in the molecular pathogenesis of HPV
M Thomas, D Pim, L Banks - Oncogene, 1999 - nature.com
Human papillomaviruses (HPVs) are associated with a number of clinical conditions, of
which the most serious is cervical carcinoma. The E6 protein of the oncogenic, mucosal …
which the most serious is cervical carcinoma. The E6 protein of the oncogenic, mucosal …
Specific interaction between HPV-16 E1–E4 and cytokeratins results in collapse of the epithelial cell intermediate filament network
J Doorbar, S Ely, J Sterling, C McLean, L Crawford - Nature, 1991 - nature.com
THE human papillomaviruses (HPV) are associated specifically with epithelial lesions,
ranging from benign warts to invasive carcinoma (for review, see refs 1, 2). The virus …
ranging from benign warts to invasive carcinoma (for review, see refs 1, 2). The virus …
Disruption of either the E1 or the E2 regulatory gene of human papillomavirus type 16 increases viral immortalization capacity.
H Romanczuk, PM Howley - Proceedings of the National …, 1992 - National Acad Sciences
The" high-risk" human papillomavirus types 16 (HPV-16) and 18 (HPV-18) have been
etiologically implicated in the majority of human cervical carcinomas. In these cancers, the …
etiologically implicated in the majority of human cervical carcinomas. In these cancers, the …
[HTML][HTML] Cellular transformation by human papillomaviruses: lessons learned by comparing high-and low-risk viruses
AJ Klingelhutz, A Roman - Virology, 2012 - Elsevier
The oncogenic potential of papillomaviruses (PVs) has been appreciated since the 1930s
yet the mechanisms of virally-mediated cellular transformation are still being revealed …
yet the mechanisms of virally-mediated cellular transformation are still being revealed …