Cells contain molecules, which become fluorescent when excited by UV/Vis radiation of
suitable wavelength. This fluorescence emission, arising from endogenous fluorophores, is …

▪ Abstract The interaction of light within tissue has been used to recognize disease since the
mid-1800s. The recent developments of small light sources, detectors, and fiber optic probes …

Abbreviations: ACF, aberrant crypt foci; ALA, 5-aminolevulinic acid; AIS4PC, tetrasulfonated
chloroaluminum phthalocyanine; antiCEA MoAb, anticarcinoembryonic antigen; BBC, basal …

Fast and non-invasive, diagnostic techniques based on fluorescence spectroscopy have the
potential to link the biochemical and morphologic properties of tissues to individual patient …

Optical spectroscopy has been extensively studied as a potential in vivo diagnostic tool that
can provide information about both the chemical and morphologic structure of tissue in near …

Fiber optic probes are a key element for biomedical spectroscopic sensing. We review the
use of fiber optic probes for optical spectroscopy, focusing on applications in turbid media …

Background & Aims: The aim of this study was to assess the potential of 3 spectroscopic
techniques (fluorescence, reflectance, and light-scattering spectroscopy) individually and in …

We review the application of fluorescence spectroscopy and elastic-scattering spectroscopy,
over the ultraviolet-to-visible wavelength range, to minimally invasive medical diagnostics …

In vivo autofluorescence spectra were obtained in 5 patients with carcinoma in situ, 26
patients with invasive tumors, and 1 patient with severe dysplasia. Significant spectral …

Written by more than 400 subject experts representing diverse academic and applied
domains, this multidisciplinary resource surveys the vanguard of biomaterials and …