Prostate cancer is the most frequent nonskin cancer and second most common cause of
cancer-related deaths in man. Prostate cancer is a clinically heterogeneous disease with …

Prostate cancer remains one of the most lethal malignancies among men worldwide.
Although the primary tumor can be successfully managed by surgery and radiotherapy …

Cancer cells proliferate, differentiate and migrate by repurposing physiological signalling
mechanisms. In particular, altered calcium signalling is emerging as one of the most …

Prostate cancer (PCa) is the most commonly diagnosed cancer among men in western
countries. Androgen receptor (AR) signaling plays key roles in the development of PCa …

Prostate cancer (PCa) is the second most common cause of cancer‐related mortality in men
in the United States. The androgen receptor (AR) and the physiological pathways it …

The liver plays a crucial role in a variety of physiological processes. Sexual dimorphism is
markedly defined in liver disorders, such as fatty liver diseases and liver cancer, but barely …

Castration-resistant prostate cancer (CRPC) emerges after androgen withdrawal therapy
and remains incurable due to the lack of effective treatment protocols. Treatment with …

Enzalutamide is an effective drug for the treatment of castration-resistant prostate cancer
(CRPC), but acquired enzalutamide resistance is usually unavoidable within the short term …

Since the authors first reviewed this subject in 2016 significant progress has been
documented in the CCN field with advances made in the understanding of how members of …

Androgen receptor (AR), a hormonal transcription factor, plays important roles during
prostate cancer progression and is a key target for therapeutic interventions. While …