IL-6 and IL-8: an overview of their roles in healthy and pathological pregnancies

A Vilotić, M Nacka-Aleksić, A Pirković… - International journal of …, 2022 - mdpi.com
Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Neurodevelopmental resilience and susceptibility to maternal immune activation

U Meyer - Trends in neurosciences, 2019 - cell.com
Maternal immune activation (MIA), be it triggered by infectious or noninfectious stimuli, is
implicated in various psychiatric and neurological disorders with developmental etiologies …

Maternal immune activation by poly I: C as a preclinical model for neurodevelopmental disorders: a focus on autism and schizophrenia

FL Haddad, SV Patel, S Schmid - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
Maternal immune activation (MIA) in response to a viral infection during early and mid-
gestation has been linked through various epidemiological studies to a higher risk for the …

Inflammation and the potential implication of macrophage-microglia polarization in human ASD: an overview

N Lampiasi, R Bonaventura, I Deidda, F Zito… - International Journal of …, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a heterogeneous collection of neurodevelopmental
disorders, difficult to diagnose and currently lacking treatment options. The possibility of …

Maternal immune activation and the development of dopaminergic neurotransmission of the offspring: relevance for schizophrenia and other psychoses

A Aguilar-Valles, B Rodrigue… - Frontiers in Psychiatry, 2020 - frontiersin.org
Prenatal infections have been linked to the development of schizophrenia (SCZ) and other
neurodevelopmental disorders in the offspring, and work in animal models indicates that this …

Maternal immune conditions are increased in males with autism spectrum disorders and are associated with behavioural and emotional but not cognitive co-morbidity

S Patel, RC Dale, D Rose, B Heath, CW Nordahl… - Translational …, 2020 - nature.com
Epidemiological and animal research shows that maternal immune activation increases the
risk of autism spectrum disorders (ASD) in offspring. Emerging evidence suggests that …

Maternal obesity, gestational diabetes mellitus, and diet in association with neurodevelopment of 2-year-old children

L Saros, A Lind, S Setänen, K Tertti, E Koivuniemi… - Pediatric …, 2023 - nature.com
Background Maternal metabolic disturbances and diet may influence long-term infantile
neurodevelopment. We investigated whether maternal gestational diabetes mellitus (GDM) …

Persistently high levels of maternal antenatal inflammation are associated with and mediate the effect of prenatal environmental adversities on neurodevelopmental …

P Girchenko, M Lahti-Pulkkinen, K Heinonen… - Biological …, 2020 - Elsevier
Background Prenatal exposure to environmental adversities, including maternal
overweight/obesity, diabetes/hypertensive disorders, or mood/anxiety disorders, increases …

Early environmental upheaval and the risk for schizophrenia

V Paquin, M Lapierre, F Veru… - Annual Review of Clinical …, 2021 - annualreviews.org
Why does prenatal exposure to wars, natural disasters, urbanicity, or winter increase the risk
for schizophrenia? Research from the last two decades has provided rich insight about the …

Placental inflammatory cytokines mRNA expression and preschool children's cognitive performance: a birth cohort study in China

J Zhou, J Tong, X Ru, Y Teng, M Geng, S Yan, F Tao… - BMC medicine, 2023 - Springer
Background The immunologic milieu at the maternal–fetal interface has profound effects on
propelling the development of the fetal brain. However, accessible epidemiological studies …