Recent development of gold (I) and gold (III) complexes as therapeutic agents for cancer diseases

Y Lu, X Ma, X Chang, Z Liang, L Lv, M Shan… - Chemical Society …, 2022 - pubs.rsc.org
Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …

[HTML][HTML] Gold as a possible alternative to platinum-based chemotherapy for colon cancer treatment

I Mármol, J Quero, MJ Rodríguez-Yoldi, E Cerrada - Cancers, 2019 - mdpi.com
Due to the increasing incidence and high mortality associated with colorectal cancer (CRC),
novel therapeutic strategies are urgently needed. Classic chemotherapy against CRC is …

Synthesis, characterization, photoluminescence, anti-tumor activity, DFT calculations and molecular docking with proteins of zinc (II) halogen substituted terpyridine …

X Liang, J Jiang, X Xue, L Huang, X Ding, D Nong… - Dalton …, 2019 - pubs.rsc.org
Reactions between halogen substituted terpyridine ligands F-(L1), Cl-(L2), Br-(L3) and I-4′-
phenyl-terpyridine (L4) and ZnBr2 or ZnI2 led to the formation of complexes [Zn (Br) …

Alkynyl Gold (I) complexes derived from 3-hydroxyflavones as multi-targeted drugs against colon cancer

I Mármol, P Castellnou, R Alvarez, MC Gimeno… - European journal of …, 2019 - Elsevier
The design of multi-targeted drugs has gained considerable interest in the last decade
thanks to their advantages in the treatment of different diseases, including cancer. The …

Synthesis, characterization, antimicrobial, BSA binding, DFT calculation, molecular docking and cytotoxicity of Ni (II) complexes with Schiff base ligands

JJ Rani, AMI Jayaseeli, S Rajagopal… - Journal of Molecular …, 2021 - Elsevier
A series of a tetradentate N 2 O 2 Schiff base ligands (1a-e),[N, N′-(X) bis (salicylidene) 1,
2-phenylenediamine], salphens {where X= H (1a), Cl (1b), Br (1c), CH 3 (1d), OCH 3 (1e)} …

[HTML][HTML] The backbone of success of P, N-hybrid ligands: Some recent developments

MB Smith - Molecules, 2022 - mdpi.com
Organophosphorus ligands are an invaluable family of compounds that continue to underpin
important roles in disciplines such as coordination chemistry and catalysis. Their success …

Proteasome versus thioredoxin reductase competition as possible biological targets in antitumor mixed thiolate-dithiocarbamate gold (III) complexes

J Quero, S Cabello, T Fuertes, I Mármol… - Inorganic …, 2018 - ACS Publications
New mixed gold (III) derivatives with dithiocarbamate and thiolate ligands have been
synthesized and characterized. They display high anticancer activity against colon cancer …

Cadmium (II) coordination polymer based on flexible dithiolate-polyamine binary ligands system: crystal structure, Hirshfeld surface analysis, antimicrobial, and DNA …

T Bhattacharjee, S Adhikari, A Datta, CG Daniliuc… - Polyhedron, 2022 - Elsevier
The mononuclear chelating complex [Cd (i-mnt)(tren)] n (1) fabricated from binary ligand
systems 1, 1-dicyanoethylene-2, 2-dithiolate (i-mnt− 2) and diethylenetriamine (tren) has …

Synthesis of novel caffeic acid derivatives and their protective effect against hydrogen peroxide induced oxidative stress via Nrf2 pathway

X Peng, G Wu, A Zhao, K Huang, L Chai, B Natarajan… - Life sciences, 2020 - Elsevier
Aim This study was aimed to synthesize novel caffeic acid derivatives and evaluate their
potential applications for the treatment of oxidative stress associated disease. Main methods …

[HTML][HTML] Selective anticancer and antimicrobial metallodrugs based on gold (Iii) dithiocarbamate complexes

E Abás, D Aguirre-Ramírez, M Laguna, L Grasa - Biomedicines, 2021 - mdpi.com
New dithiocarbamate cycloaurated complexes have been synthesized and their
physicochemical and in vitro antitumor properties have been evaluated. All the performed …