Recent development of gold (I) and gold (III) complexes as therapeutic agents for cancer diseases
Y Lu, X Ma, X Chang, Z Liang, L Lv, M Shan… - Chemical Society …, 2022 - pubs.rsc.org
Metal complexes have demonstrated significant antitumor activities and platinum complexes
are well established in the clinical application of cancer chemotherapy. However, the …
are well established in the clinical application of cancer chemotherapy. However, the …
[HTML][HTML] Gold as a possible alternative to platinum-based chemotherapy for colon cancer treatment
Due to the increasing incidence and high mortality associated with colorectal cancer (CRC),
novel therapeutic strategies are urgently needed. Classic chemotherapy against CRC is …
novel therapeutic strategies are urgently needed. Classic chemotherapy against CRC is …
Synthesis, characterization, photoluminescence, anti-tumor activity, DFT calculations and molecular docking with proteins of zinc (II) halogen substituted terpyridine …
X Liang, J Jiang, X Xue, L Huang, X Ding, D Nong… - Dalton …, 2019 - pubs.rsc.org
Reactions between halogen substituted terpyridine ligands F-(L1), Cl-(L2), Br-(L3) and I-4′-
phenyl-terpyridine (L4) and ZnBr2 or ZnI2 led to the formation of complexes [Zn (Br) …
phenyl-terpyridine (L4) and ZnBr2 or ZnI2 led to the formation of complexes [Zn (Br) …
Alkynyl Gold (I) complexes derived from 3-hydroxyflavones as multi-targeted drugs against colon cancer
The design of multi-targeted drugs has gained considerable interest in the last decade
thanks to their advantages in the treatment of different diseases, including cancer. The …
thanks to their advantages in the treatment of different diseases, including cancer. The …
Synthesis, characterization, antimicrobial, BSA binding, DFT calculation, molecular docking and cytotoxicity of Ni (II) complexes with Schiff base ligands
JJ Rani, AMI Jayaseeli, S Rajagopal… - Journal of Molecular …, 2021 - Elsevier
A series of a tetradentate N 2 O 2 Schiff base ligands (1a-e),[N, N′-(X) bis (salicylidene) 1,
2-phenylenediamine], salphens {where X= H (1a), Cl (1b), Br (1c), CH 3 (1d), OCH 3 (1e)} …
2-phenylenediamine], salphens {where X= H (1a), Cl (1b), Br (1c), CH 3 (1d), OCH 3 (1e)} …
[HTML][HTML] The backbone of success of P, N-hybrid ligands: Some recent developments
MB Smith - Molecules, 2022 - mdpi.com
Organophosphorus ligands are an invaluable family of compounds that continue to underpin
important roles in disciplines such as coordination chemistry and catalysis. Their success …
important roles in disciplines such as coordination chemistry and catalysis. Their success …
Proteasome versus thioredoxin reductase competition as possible biological targets in antitumor mixed thiolate-dithiocarbamate gold (III) complexes
J Quero, S Cabello, T Fuertes, I Mármol… - Inorganic …, 2018 - ACS Publications
New mixed gold (III) derivatives with dithiocarbamate and thiolate ligands have been
synthesized and characterized. They display high anticancer activity against colon cancer …
synthesized and characterized. They display high anticancer activity against colon cancer …
Cadmium (II) coordination polymer based on flexible dithiolate-polyamine binary ligands system: crystal structure, Hirshfeld surface analysis, antimicrobial, and DNA …
The mononuclear chelating complex [Cd (i-mnt)(tren)] n (1) fabricated from binary ligand
systems 1, 1-dicyanoethylene-2, 2-dithiolate (i-mnt− 2) and diethylenetriamine (tren) has …
systems 1, 1-dicyanoethylene-2, 2-dithiolate (i-mnt− 2) and diethylenetriamine (tren) has …
Synthesis of novel caffeic acid derivatives and their protective effect against hydrogen peroxide induced oxidative stress via Nrf2 pathway
X Peng, G Wu, A Zhao, K Huang, L Chai, B Natarajan… - Life sciences, 2020 - Elsevier
Aim This study was aimed to synthesize novel caffeic acid derivatives and evaluate their
potential applications for the treatment of oxidative stress associated disease. Main methods …
potential applications for the treatment of oxidative stress associated disease. Main methods …
[HTML][HTML] Selective anticancer and antimicrobial metallodrugs based on gold (Iii) dithiocarbamate complexes
New dithiocarbamate cycloaurated complexes have been synthesized and their
physicochemical and in vitro antitumor properties have been evaluated. All the performed …
physicochemical and in vitro antitumor properties have been evaluated. All the performed …