Four decades of ischemic penumbra and its implication for ischemic stroke
SH Yang, R Liu - Translational stroke research, 2021 - Springer
The ischemic penumbra defined four decades ago has been the main battleground of
ischemic stroke. The evolving ischemic penumbra concept has been providing insight for the …
ischemic stroke. The evolving ischemic penumbra concept has been providing insight for the …
Advances in acute ischemic stroke treatment: Current status and future directions
The management of acute ischemic stroke has undergone a paradigm shift in the past
decade. This has been spearheaded by the emergence of endovascular thrombectomy …
decade. This has been spearheaded by the emergence of endovascular thrombectomy …
Collateral circulation in thrombectomy for stroke after 6 to 24 hours in the DAWN trial
Background and Purpose: Collaterals govern the pace and severity of cerebral ischemia,
distinguishing fast or slow progressors and corresponding therapeutic opportunities. The …
distinguishing fast or slow progressors and corresponding therapeutic opportunities. The …
Relative cerebral blood flow as an indirect imaging surrogate in patients with anterior circulation large vessel occlusion and association of baseline characteristics with …
Background In acute ischemic stroke (AIS), collateral status (CS) is an important predictor of
favorable outcomes in patients with AIS. Among quantitative cerebral perfusion parameters …
favorable outcomes in patients with AIS. Among quantitative cerebral perfusion parameters …
High-definition cathodal direct current stimulation for treatment of acute ischemic stroke: a randomized clinical trial
Importance Cathodal transcranial direct current stimulation (C-tDCS) provides
neuroprotection in preclinical models of acute ischemic stroke (AIS) by inhibiting peri-infarct …
neuroprotection in preclinical models of acute ischemic stroke (AIS) by inhibiting peri-infarct …
Accuracy of CT perfusion–based core estimation of follow-up infarction: effects of time since last known well
A Sarraj, BCV Campbell, S Christensen, CW Sitton… - Neurology, 2022 - AAN Enterprises
Background and Objectives To assess the accuracy of baseline CT perfusion (CTP)
ischemic core estimates. Methods From SELECT (Optimizing Patient Selection for …
ischemic core estimates. Methods From SELECT (Optimizing Patient Selection for …
Diabetes mellitus/poststroke hyperglycemia: a detrimental factor for tPA thrombolytic stroke therapy
Intravenous administration of tissue-type plasminogen activator (IV tPA) therapy has long
been considered a mainstay in ischemic stroke management. However, patients respond to …
been considered a mainstay in ischemic stroke management. However, patients respond to …
Integrative physiological assessment of cerebral hemodynamics and metabolism in acute ischemic stroke
JL Fan, RC Nogueira, P Brassard… - Journal of Cerebral …, 2022 - journals.sagepub.com
Restoring perfusion to ischemic tissue is the primary goal of acute ischemic stroke care, yet
only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is …
only a small portion of patients receive reperfusion treatment. Since blood pressure (BP) is …
The compensation index is better associated with DSA ASITN collateral score compared to the cerebral blood volume index and hypoperfusion intensity ratio
Background: Pretreatment CT Perfusion (CTP) parameters serve as reliable surrogates of
collateral status (CS). In this study, we aim to assess the relationship between the novel …
collateral status (CS). In this study, we aim to assess the relationship between the novel …
Collateral blood flow and ischemic core growth
K Seifert, JJ Heit - Translational Stroke Research, 2023 - Springer
Abstract Treatment of a large vessel occlusion in the acute ischemic stroke setting focuses
on vessel recanalization, and endovascular thrombectomy results in favorable outcomes in …
on vessel recanalization, and endovascular thrombectomy results in favorable outcomes in …