Bidirectional microglia–neuron communication in health and disease

Z Szepesi, O Manouchehrian, S Bachiller… - Frontiers in cellular …, 2018 - frontiersin.org
Microglia are ramified cells that exhibit highly motile processes, which continuously survey
the brain parenchyma and react to any insult to the CNS homeostasis. Although microglia …

Microglia-astrocyte crosstalk: an intimate molecular conversation

MK Jha, M Jo, JH Kim, K Suk - The Neuroscientist, 2019 - journals.sagepub.com
Microglia-astrocyte crosstalk has recently been at the forefront of glial research. Emerging
evidence illustrates that microglia-and astrocyte-derived signals are the functional …

Exosomes derived from bone-marrow mesenchymal stem cells alleviate cognitive decline in AD-like mice by improving BDNF-related neuropathology

S Liu, M Fan, JX Xu, LJ Yang, CC Qi, QR Xia… - Journal of …, 2022 - Springer
Background Alzheimer's disease (AD) is a neurodegenerative disease characterized by a
progressive decline in cognitive ability. Exosomes derived from bone-marrow mesenchymal …

Estrogens, neuroinflammation, and neurodegeneration

A Villa, E Vegeto, A Poletti, A Maggi - Endocrine reviews, 2016 - academic.oup.com
Inflammatory activation of microglia is a hallmark of several disorders of the central nervous
system. In addition to protecting the brain against inflammatory insults, microglia are …

[HTML][HTML] Properties and behavior of carbon nanomaterials when interfacing neuronal cells: How far have we come?

R Rauti, M Musto, S Bosi, M Prato, L Ballerini - Carbon, 2019 - Elsevier
In the last two decades, an increasing amount of studies have investigated the use of
components based on carbon-(nano) materials in the engineering of neural interfaces, to …

Systemic inflammation and the brain: novel roles of genetic, molecular, and environmental cues as drivers of neurodegeneration

R Sankowski, S Mader… - Frontiers in cellular …, 2015 - frontiersin.org
The nervous and immune systems have evolved in parallel from the early bilaterians, in
which innate immunity and a central nervous system (CNS) coexisted for the first time, to …

Neuroinflammation: an integrating overview of reactive‐Neuroimmune cell interactions in health and disease

R Kölliker-Frers, L Udovin… - Mediators of …, 2021 - Wiley Online Library
The concept of central nervous system (CNS) inflammation has evolved over the last
decades. Neuroinflammation is the response of reactive CNS components to altered …

Chimeric antigen receptor T cell–mediated neurotoxicity in nonhuman primates

A Taraseviciute, V Tkachev, R Ponce, CJ Turtle… - Cancer discovery, 2018 - AACR
Chimeric antigen receptor (CAR) T-cell immunotherapy has revolutionized the treatment of
refractory leukemias and lymphomas, but is associated with significant toxicities, namely …

Crosstalk between neuron and glial cells in oxidative injury and neuroprotection

KH Lee, M Cha, BH Lee - International Journal of Molecular Sciences, 2021 - mdpi.com
To counteract oxidative stress and associated brain diseases, antioxidant systems rescue
neuronal cells from oxidative stress by neutralizing reactive oxygen species and preserving …

Neutrophil‐to‐Lymphocyte Ratio and Early Neurological Deterioration in Stroke Patients: A Systematic Review and Meta‐Analysis

S Sarejloo, H Kheradjoo, S Es Haghi… - BioMed Research …, 2022 - Wiley Online Library
In light of the growing emphasis on classifying stroke patients for different levels of
monitoring intensity and emergency treatments, we conducted a systematic review of a wide …