Negative social experiences during adolescence are central features for several stress-
related mental illnesses. Social play fighting behavior in rats peaks during early …

In this review we propose that there are sex differences in how men and women enter onto
the path that can lead to addiction. Males are more likely than females to engage in risky …

Rationale Research on adolescence and drug abuse increased substantially in the past
decade. However, drug-addiction-related behaviors following stressful experiences during …

Background The plenary session at the 2016 Behavior, Biology and Chemistry:
Translational Research in Addiction Conference focused on glia as potential players in the …

There is growing recognition that glial proinflammatory activation importantly contributes to
the rewarding and reinforcing effects of a variety of drugs of abuse, including cocaine …

Background The link between adolescent social stress and substance abuse is modeled in
social defeat of adolescent male rats, at an age when social experiences are essential for …

In drug users, drug-related cues alone can induce dopamine release in the dorsal striatum.
Instructive cues activate inputs to the striatum from both dopaminergic and cholinergic …

Introduction: Preclinical literature, frequently utilizing rats, suggests females display a more
rapid advancement of substance abuse and a greater risk of relapse following drug …

Rationale Women are more sensitive than men to psychostimulants and progress from initial
use to drug addiction more quickly. The mouse has been an under-utilized model to study …

Women acquire cocaine habits faster and are more motivated to obtain drug than men. In
general, female rodents acquire intravenous cocaine self-administration (SA) faster and …